Factors leading to obstructive granulation tissue formation after ultraflex stenting in benign tracheal narrowing

F. T. Chung, S. M. Lin, C. L. Chou, H. C. Chen, C. T. Yu, H. P. Kuo

研究成果: 雜誌貢獻文章同行評審

33 引文 斯高帕斯(Scopus)

摘要

Background: This retrospective study aimed to determine the factors leading to obstructive granulation tissue formation after the placement of a self-expandable metallic stent (SEMS) in patients with benign tracheal disease. Methods: From 2001 to 2007, a total of 67 patients (age: 62.1±15.4 years; range: 2387 years) with benign tracheal disease received 75ultraflex SEMS in our institution. Results: There were 35 SEMSs complicated by obstructive granulation tissue formation out of the 75 stents placed in patients with tracheal disease, giving an incidence of 47.8% (32/67 patients). The median time until developing granulation tissue was 106 days (IQR, 46396). Structural airway obstruction prior to SEMS implantation independently predicted obstructive granulation tissue formation after SEMS implantation (odds ratio: 3.84; 95% CI: 1.018.7; p=0.04). Time to granulation tissue detection was shorter in patients with structural airway obstruction before SEMS implantation (structural airway obstruction vs. dynamic collapse airway: median [IQR] 95 [38224, n=26] vs. 396 days [73994, n=9]; p=0.02). Conclusions: Obstructive granulation tissue formation is not uncommon after SEMS implantation and structural airway obstruction prior to SEMS implantation is an independent predictor. Although SEMS implantation should be restricted to a select population, it may be placed in patients not suitable for surgical intervention or rigid bronchoscopy with anesthesia because of poor pulmonary function.
原文英語
頁(從 - 到)102-107
頁數6
期刊Thoracic and Cardiovascular Surgeon
58
發行號2
DOIs
出版狀態已發佈 - 三月 31 2010
對外發佈

Keywords

  • Benign tracheal stenosis
  • Obstructive granulation tissue
  • Selfexpandable metallic stents
  • Ultraflex

ASJC Scopus subject areas

  • 手術
  • 肺和呼吸系統醫學
  • 心臟病學與心血管醫學

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