Factors associated with voiding function in women with lower urinary tract symptoms: A mathematic model explanation

研究成果: 雜誌貢獻文章

7 引文 (Scopus)

摘要

Aims. The aim of this study was to explore the relationship between voiding function and factors such as age, gravidity, parity, menopause, and anterior vaginal wall relaxation. Methods. One hundred twenty-five women were identified from urodynamic records, 83 premenopausal and 42 postmenopausal. All had had a sonographic assessment of the lower urinary tract and a full urodynamic study, including a pressure-flow study. None had diabetes mellitus, overt neurologic disease, pelvic surgery, anticholinergic medication or estrogen therapy, or voiding difficulty symptoms. Voiding parameters included the following urodynamic variables: maximum flow rate, average flow rate, residual urine, the ratio of residual urine to total bladder volume on spontaneous uroflowmetry, maximum flow rate, and detrusor pressure at maximum flow on a pressure-flow study. Results. Uroflow rates were significantly correlated with age, parity, and urethral mobility. As a whole, the scatter plots of maximum and average flow rates versus voided volume on uroflowmetry displayed a significant correlation (P <0.0001 and P <0.0001, respectively). But, there was no association between maximum flow rate and detrusor pressure at maximum flow in the pressure flow study (P = 0.132). Age, menopause, parity, and urethral mobility may have affected the correlation on uroflowmetry but have no effect on pressure-flow plot. On subgroup analysis, significant correlation was identified only in women aged between 30 and 70, with parity greater than three, and urethral mobility greater than 70 degrees. These groups all had a reduced urethral pressure profile. Conclusions. Age, menopause, parity, and urethral mobility may change the hydrodynamics of the lower urinary tract and have varying impact on the voiding function by altering urethral distensibility. Moreover, poor detrusor power in the postmenopausal women may complicate the analysis of voiding function.
原文英語
頁(從 - 到)574-581
頁數8
期刊Neurourology and Urodynamics
22
發行號6
DOIs
出版狀態已發佈 - 2003
對外發佈Yes

指紋

Lower Urinary Tract Symptoms
Mathematics
Parity
Pressure
Urodynamics
Menopause
Urinary Tract
Urine
Gravidity
Cholinergic Antagonists
Hydrodynamics
Nervous System Diseases
Diabetes Mellitus
Estrogens
Urinary Bladder

ASJC Scopus subject areas

  • Nephrology
  • Clinical Neurology
  • Urology

引用此文

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title = "Factors associated with voiding function in women with lower urinary tract symptoms: A mathematic model explanation",
abstract = "Aims. The aim of this study was to explore the relationship between voiding function and factors such as age, gravidity, parity, menopause, and anterior vaginal wall relaxation. Methods. One hundred twenty-five women were identified from urodynamic records, 83 premenopausal and 42 postmenopausal. All had had a sonographic assessment of the lower urinary tract and a full urodynamic study, including a pressure-flow study. None had diabetes mellitus, overt neurologic disease, pelvic surgery, anticholinergic medication or estrogen therapy, or voiding difficulty symptoms. Voiding parameters included the following urodynamic variables: maximum flow rate, average flow rate, residual urine, the ratio of residual urine to total bladder volume on spontaneous uroflowmetry, maximum flow rate, and detrusor pressure at maximum flow on a pressure-flow study. Results. Uroflow rates were significantly correlated with age, parity, and urethral mobility. As a whole, the scatter plots of maximum and average flow rates versus voided volume on uroflowmetry displayed a significant correlation (P <0.0001 and P <0.0001, respectively). But, there was no association between maximum flow rate and detrusor pressure at maximum flow in the pressure flow study (P = 0.132). Age, menopause, parity, and urethral mobility may have affected the correlation on uroflowmetry but have no effect on pressure-flow plot. On subgroup analysis, significant correlation was identified only in women aged between 30 and 70, with parity greater than three, and urethral mobility greater than 70 degrees. These groups all had a reduced urethral pressure profile. Conclusions. Age, menopause, parity, and urethral mobility may change the hydrodynamics of the lower urinary tract and have varying impact on the voiding function by altering urethral distensibility. Moreover, poor detrusor power in the postmenopausal women may complicate the analysis of voiding function.",
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T1 - Factors associated with voiding function in women with lower urinary tract symptoms

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AU - Yang, Jenn Ming

AU - Huang, Wen Chen

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N2 - Aims. The aim of this study was to explore the relationship between voiding function and factors such as age, gravidity, parity, menopause, and anterior vaginal wall relaxation. Methods. One hundred twenty-five women were identified from urodynamic records, 83 premenopausal and 42 postmenopausal. All had had a sonographic assessment of the lower urinary tract and a full urodynamic study, including a pressure-flow study. None had diabetes mellitus, overt neurologic disease, pelvic surgery, anticholinergic medication or estrogen therapy, or voiding difficulty symptoms. Voiding parameters included the following urodynamic variables: maximum flow rate, average flow rate, residual urine, the ratio of residual urine to total bladder volume on spontaneous uroflowmetry, maximum flow rate, and detrusor pressure at maximum flow on a pressure-flow study. Results. Uroflow rates were significantly correlated with age, parity, and urethral mobility. As a whole, the scatter plots of maximum and average flow rates versus voided volume on uroflowmetry displayed a significant correlation (P <0.0001 and P <0.0001, respectively). But, there was no association between maximum flow rate and detrusor pressure at maximum flow in the pressure flow study (P = 0.132). Age, menopause, parity, and urethral mobility may have affected the correlation on uroflowmetry but have no effect on pressure-flow plot. On subgroup analysis, significant correlation was identified only in women aged between 30 and 70, with parity greater than three, and urethral mobility greater than 70 degrees. These groups all had a reduced urethral pressure profile. Conclusions. Age, menopause, parity, and urethral mobility may change the hydrodynamics of the lower urinary tract and have varying impact on the voiding function by altering urethral distensibility. Moreover, poor detrusor power in the postmenopausal women may complicate the analysis of voiding function.

AB - Aims. The aim of this study was to explore the relationship between voiding function and factors such as age, gravidity, parity, menopause, and anterior vaginal wall relaxation. Methods. One hundred twenty-five women were identified from urodynamic records, 83 premenopausal and 42 postmenopausal. All had had a sonographic assessment of the lower urinary tract and a full urodynamic study, including a pressure-flow study. None had diabetes mellitus, overt neurologic disease, pelvic surgery, anticholinergic medication or estrogen therapy, or voiding difficulty symptoms. Voiding parameters included the following urodynamic variables: maximum flow rate, average flow rate, residual urine, the ratio of residual urine to total bladder volume on spontaneous uroflowmetry, maximum flow rate, and detrusor pressure at maximum flow on a pressure-flow study. Results. Uroflow rates were significantly correlated with age, parity, and urethral mobility. As a whole, the scatter plots of maximum and average flow rates versus voided volume on uroflowmetry displayed a significant correlation (P <0.0001 and P <0.0001, respectively). But, there was no association between maximum flow rate and detrusor pressure at maximum flow in the pressure flow study (P = 0.132). Age, menopause, parity, and urethral mobility may have affected the correlation on uroflowmetry but have no effect on pressure-flow plot. On subgroup analysis, significant correlation was identified only in women aged between 30 and 70, with parity greater than three, and urethral mobility greater than 70 degrees. These groups all had a reduced urethral pressure profile. Conclusions. Age, menopause, parity, and urethral mobility may change the hydrodynamics of the lower urinary tract and have varying impact on the voiding function by altering urethral distensibility. Moreover, poor detrusor power in the postmenopausal women may complicate the analysis of voiding function.

KW - Pressure flow study

KW - Uroflowmetry

KW - Voiding function

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