Fabrication of microfluidic chip using micro-hot embossing with micro electrical discharge machining mold

Mao Suan Huang, Yuh Chyun Chiang, Sheng Chieh Lin, Hsin Chung Cheng, Chiung Fang Huang, Yung Kang Shen, Yi Lin

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)


This study develops an improved method for generating aluminum mold inserts used in the replication of polymer-based microfluidic chip. Since molding masters that are suitable for microfluidic chip replication must have features whose dimensions are of the order of tens to hundreds of microns, micro electrical discharge machining is employed herein to fabricate an aluminum mold insert of a microfluidic chip. The width and depth of the aluminum mold insert for the microfluidic chip are 61.50 and 49.61μm, respectively. The surface roughness values of the microchannel and the sample reservoir in aluminum mold insert for the microfluidic chip are 53.9 and 34.3nm, respectively. PMMA material is adopted as the molded microfluidic chip that is produced by micro-hot embossing molding. The PMMA material can replicate the microchannel and sample reservoir very well when the aluminum mold insert is used in micro-hot embossing molding. The results indicate that the most important parameter in the replication of molded microfluidic chip is the embossing pressure, which is also the most important parameter in determining the surface roughness of the molded microfluidic chip.
頁(從 - 到)57-64
期刊Polymers for Advanced Technologies
出版狀態已發佈 - 一月 2012


ASJC Scopus subject areas

  • Polymers and Plastics