Extracellular ATP activates the PLC/PKC/ERK signaling pathway through the P2Y2 purinergic receptor leading to the induction of early growth response 1 expression and the inhibition of viability in human endometrial stromal cells

Medicine & Life Sciences

• Purinergic P2Y2 Receptors 100%
• Type C Phospholipases 72%
• MAP Kinase Signaling System 71%
• Stromal Cells 65%
• Protein Kinase C 61%
• Adenosine Triphosphate 50%
• Growth 32%
• Mitogen-Activated Protein Kinases 28%
• Cell Survival 21%
• Immediate-Early Genes 17%
• Purinergic P2 Receptor Antagonists 12%
• Diacylglycerol Kinase 10%
• Suramin 9%
• Uridine Triphosphate 9%
• Neomycin 9%
• Genes 8%
• Gene Expression 8%
• Protein C Inhibitor 8%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 8%
• Mitogen-Activated Protein Kinase Kinases 7%
• Protein Kinase Inhibitors 7%
• G-Protein-Coupled Receptors 7%
• Western Blotting 4%