Exophthalmos of patients with Graves' disease in Chinese of Taiwan

C. C. Tsai, H. C. Kau, S. C. Kao, Wen-Ming Hsu

研究成果: 雜誌貢獻文章

43 引文 (Scopus)

摘要

Purpose: To determine the exophthalmos measurements in patients with Graves' disease (GD) and to compare with those of normal subjects among the Chinese of Taiwan. Methods: Hertel's exophthalmometry were performed in 163 consecutive adult GD patients and 419 normal subjects. The values of exophthalmos, asymmetry, and the distance between lateral orbital rims (base) were evaluated. Results: There was a significant difference between GD and normal adults for exophthalmos and asymmetry, with GD patients demonstrating a mean exophthalmos of 18.32 mm and asymmetry of 0.93 mm as compared with 13.91 and 0.55 mm for normal subjects (P< 0.001). The mean value of base for GD adults (106.52 mm) is slightly greater than normal subjects (105.82 mm). There was no gender difference in exophthalmometric value or asymmetry in each group. A total of 79 (48.5%) GD patients had exophthalmos greater than the upper limit of normal Chinese in Taiwan (18.6 mm). Asymmetry over 2 mm was observed in 11 (6.7%) patients with GD but in none of the normal subjects. Conclusions: GD patients have significant exophthalmos and asymmetry compared to normal subjects. In comparison with previous studies, exophthalmos values for Chinese in Taiwan tend to be lower than those of Caucasians and black-American people, but are close to those of Korean, Japanese, Iranian, Indian, and Asian-American people. Adequate adjustment of normal and abnormal values of exophthalmos according to individual differences is important for the diagnosis of orbital morbidity and management of thyroid associated orbitopathy.

原文英語
頁(從 - 到)569-573
頁數5
期刊Eye
20
發行號5
DOIs
出版狀態已發佈 - 一月 1 2006
對外發佈Yes

指紋

Exophthalmos
Graves Disease
Taiwan
Social Adjustment
Asian Americans
Individuality
Asymmetry
Thyroid Gland
Reference Values
Morbidity

ASJC Scopus subject areas

  • Ophthalmology
  • Arts and Humanities(all)

引用此文

Exophthalmos of patients with Graves' disease in Chinese of Taiwan. / Tsai, C. C.; Kau, H. C.; Kao, S. C.; Hsu, Wen-Ming.

於: Eye, 卷 20, 編號 5, 01.01.2006, p. 569-573.

研究成果: 雜誌貢獻文章

Tsai, C. C. ; Kau, H. C. ; Kao, S. C. ; Hsu, Wen-Ming. / Exophthalmos of patients with Graves' disease in Chinese of Taiwan. 於: Eye. 2006 ; 卷 20, 編號 5. 頁 569-573.
@article{1d06ee3bf04f483bbeef39cf632ec92f,
title = "Exophthalmos of patients with Graves' disease in Chinese of Taiwan",
abstract = "Purpose: To determine the exophthalmos measurements in patients with Graves' disease (GD) and to compare with those of normal subjects among the Chinese of Taiwan. Methods: Hertel's exophthalmometry were performed in 163 consecutive adult GD patients and 419 normal subjects. The values of exophthalmos, asymmetry, and the distance between lateral orbital rims (base) were evaluated. Results: There was a significant difference between GD and normal adults for exophthalmos and asymmetry, with GD patients demonstrating a mean exophthalmos of 18.32 mm and asymmetry of 0.93 mm as compared with 13.91 and 0.55 mm for normal subjects (P< 0.001). The mean value of base for GD adults (106.52 mm) is slightly greater than normal subjects (105.82 mm). There was no gender difference in exophthalmometric value or asymmetry in each group. A total of 79 (48.5{\%}) GD patients had exophthalmos greater than the upper limit of normal Chinese in Taiwan (18.6 mm). Asymmetry over 2 mm was observed in 11 (6.7{\%}) patients with GD but in none of the normal subjects. Conclusions: GD patients have significant exophthalmos and asymmetry compared to normal subjects. In comparison with previous studies, exophthalmos values for Chinese in Taiwan tend to be lower than those of Caucasians and black-American people, but are close to those of Korean, Japanese, Iranian, Indian, and Asian-American people. Adequate adjustment of normal and abnormal values of exophthalmos according to individual differences is important for the diagnosis of orbital morbidity and management of thyroid associated orbitopathy.",
keywords = "Exophthalmos, Graves' disease, Hertel's exophthalmometry",
author = "Tsai, {C. C.} and Kau, {H. C.} and Kao, {S. C.} and Wen-Ming Hsu",
year = "2006",
month = "1",
day = "1",
doi = "10.1038/sj.eye.6701925",
language = "English",
volume = "20",
pages = "569--573",
journal = "Eye",
issn = "0950-222X",
publisher = "Nature Publishing Group",
number = "5",

}

TY - JOUR

T1 - Exophthalmos of patients with Graves' disease in Chinese of Taiwan

AU - Tsai, C. C.

AU - Kau, H. C.

AU - Kao, S. C.

AU - Hsu, Wen-Ming

PY - 2006/1/1

Y1 - 2006/1/1

N2 - Purpose: To determine the exophthalmos measurements in patients with Graves' disease (GD) and to compare with those of normal subjects among the Chinese of Taiwan. Methods: Hertel's exophthalmometry were performed in 163 consecutive adult GD patients and 419 normal subjects. The values of exophthalmos, asymmetry, and the distance between lateral orbital rims (base) were evaluated. Results: There was a significant difference between GD and normal adults for exophthalmos and asymmetry, with GD patients demonstrating a mean exophthalmos of 18.32 mm and asymmetry of 0.93 mm as compared with 13.91 and 0.55 mm for normal subjects (P< 0.001). The mean value of base for GD adults (106.52 mm) is slightly greater than normal subjects (105.82 mm). There was no gender difference in exophthalmometric value or asymmetry in each group. A total of 79 (48.5%) GD patients had exophthalmos greater than the upper limit of normal Chinese in Taiwan (18.6 mm). Asymmetry over 2 mm was observed in 11 (6.7%) patients with GD but in none of the normal subjects. Conclusions: GD patients have significant exophthalmos and asymmetry compared to normal subjects. In comparison with previous studies, exophthalmos values for Chinese in Taiwan tend to be lower than those of Caucasians and black-American people, but are close to those of Korean, Japanese, Iranian, Indian, and Asian-American people. Adequate adjustment of normal and abnormal values of exophthalmos according to individual differences is important for the diagnosis of orbital morbidity and management of thyroid associated orbitopathy.

AB - Purpose: To determine the exophthalmos measurements in patients with Graves' disease (GD) and to compare with those of normal subjects among the Chinese of Taiwan. Methods: Hertel's exophthalmometry were performed in 163 consecutive adult GD patients and 419 normal subjects. The values of exophthalmos, asymmetry, and the distance between lateral orbital rims (base) were evaluated. Results: There was a significant difference between GD and normal adults for exophthalmos and asymmetry, with GD patients demonstrating a mean exophthalmos of 18.32 mm and asymmetry of 0.93 mm as compared with 13.91 and 0.55 mm for normal subjects (P< 0.001). The mean value of base for GD adults (106.52 mm) is slightly greater than normal subjects (105.82 mm). There was no gender difference in exophthalmometric value or asymmetry in each group. A total of 79 (48.5%) GD patients had exophthalmos greater than the upper limit of normal Chinese in Taiwan (18.6 mm). Asymmetry over 2 mm was observed in 11 (6.7%) patients with GD but in none of the normal subjects. Conclusions: GD patients have significant exophthalmos and asymmetry compared to normal subjects. In comparison with previous studies, exophthalmos values for Chinese in Taiwan tend to be lower than those of Caucasians and black-American people, but are close to those of Korean, Japanese, Iranian, Indian, and Asian-American people. Adequate adjustment of normal and abnormal values of exophthalmos according to individual differences is important for the diagnosis of orbital morbidity and management of thyroid associated orbitopathy.

KW - Exophthalmos

KW - Graves' disease

KW - Hertel's exophthalmometry

UR - http://www.scopus.com/inward/record.url?scp=33646390984&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646390984&partnerID=8YFLogxK

U2 - 10.1038/sj.eye.6701925

DO - 10.1038/sj.eye.6701925

M3 - Article

C2 - 15905866

AN - SCOPUS:33646390984

VL - 20

SP - 569

EP - 573

JO - Eye

JF - Eye

SN - 0950-222X

IS - 5

ER -