Evaluation of the relationships between intravenous patient-controlled analgesia settings and morphine requirements among patients after lumbar spine surgery

Hsin Lun Wu, Mei Yung Tsou, Pei Wen Chao, Su Man Lin, Kwok Hon Chan, Kuang Yi Chang

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

摘要

To evaluate the association between daily morphine requirement and the intravenous patient-controlled analgesia (IVPCA) setting in patients undergoing spinal surgery. We conducted a retrospective analysis of 179 patients of American Society of Anesthesiologists physical status class I-III who underwent elective posterior lumbar spinal surgery and consented to IVPCA for postoperative pain control. The regi-mental solution contained morphine 1 mg/mL. The IVPCA program was set to deliver a priming dose of 1.5-4 mL, a basal infusion rate of 0-1.2 mL/hr, and a 0.5-1.5 mL bolus on demand with a 5-minute lockout interval. Demographic data, surgical procedures, analgesia program setting variables, 4-hour cumulative morphine dose and 11-point numeric rating scale for pain on postoperative days 1 and 2 were collected for comparison. The IVPCA requirement decreased gradually over time (p < 0.001). The number of vertebrae involved significantly influenced the daily morphine requirements (p = 0.01). None of the IVPCA settings, including continuous infusion, affected daily morphine requirements. On average, the analgesic requirement on postoperative day 2 was 18 less than that on postoperative day 1. The number of vertebrae involved was significantly associated with the daily IVPCA requirement. The IVPCA settings, including priming dose, basal infusion rate and bolus dose, did not affect the daily morphine requirements.
原文英語
頁(從 - 到)75-79
頁數5
期刊Acta Anaesthesiologica Taiwanica
48
發行號2
DOIs
出版狀態已發佈 - 六月 1 2010
對外發佈Yes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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