Evaluation of the hepatic and renal-protective effects of ganoderma lucidum in mice

Ying Hua Shieh, Chi Feng Liu, Yao Kuan Huang, Jen Yuann Yang, I. Lin Wu, Chia Hsien Lin, Song-Chow Lin

研究成果: 雜誌貢獻文章同行評審

44 引文 斯高帕斯(Scopus)

摘要

The antioxidative effect of hot water extract of the mushroom Ganodcrma lucidum on ethanol-induced free radical generation had been studied. In order to further investigate the hepatic and renal protective mechanism of Ganoderma lucidum, rates of lipid peroxidation were determined. The hot water extract of Ganoderma lucidum dose-dependently exhibited antioxidative effect on mouse liver and kidney lipid peroxidation; our results indicated that hepatic and renal homogenates have a higher malonic dialdehyde level in an ethanol administered group than in the Ganoderma lucidum treated group. It was concluded that the hepatic and renal protective mechanism of Ganoderma lucidum, might be due at least in part to its prominent Superoxide scavenging effect. Ganoderma extract could protect the liver and kidney from Superoxide induced hepatic and renal damages.
原文英語
頁(從 - 到)501-507
頁數7
期刊American Journal of Chinese Medicine
29
發行號3-4
DOIs
出版狀態已發佈 - 2001

ASJC Scopus subject areas

  • 補充和替代醫學

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