Evaluation of F127/chitosan hydrogel as a scaffold for bone repair

K. T. Vu Thai, M. C. Yang, W. F. Lai

研究成果: 書貢獻/報告類型會議貢獻

1 引文 斯高帕斯(Scopus)

摘要

An in situ gelled scaffold for bone tissue engineering to restore the function of bone tissues is developed. The gel is comprised of Pluronic F127 and chitosan. The gelation temperature (Tgel), and viscoelastic properties and mucoadhesive force of the systems were investigated by means of rheological analyses. At specific concentrations, the hydrogel exhibited a Tgel close to the body temperature due to the addition of chitosan. Mucoadhesion experiments showed a rheological synergism between F127/chitosan gels and mucin dispersion, and a change in the flow behavior. In vitro release results indicated that the optimized gel was able to prolong and control acyclovir release for more than 20 min. Based on cell proliferation assay, the gel exhibited biocompatibility for osteoblasts.
原文英語
主出版物標題Technical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013
頁面187-190
頁數4
3
出版狀態已發佈 - 2013
事件Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy - 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013 - Washington, DC, 美国
持續時間: 五月 12 2013五月 16 2013

會議

會議Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy - 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013
國家美国
城市Washington, DC
期間5/12/135/16/13

ASJC Scopus subject areas

  • Biotechnology

指紋 深入研究「Evaluation of F127/chitosan hydrogel as a scaffold for bone repair」主題。共同形成了獨特的指紋。

  • 引用此

    Vu Thai, K. T., Yang, M. C., & Lai, W. F. (2013). Evaluation of F127/chitosan hydrogel as a scaffold for bone repair. 於 Technical Proceedings of the 2013 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2013 (卷 3, 頁 187-190)