Erythropoietins from teleosts

C. Y. Chu; C. H. Cheng; C. H. Yang; C. J. Huang

doi:10.1007/s00018-008-8231-y

Erythropoietins from teleosts

C. Y. Chu, C. H. Cheng, C. H. Yang, C. J. Huang

生物化學暨細胞分子生物學科

研究成果: 雜誌貢獻 › 文章 › 同行評審

19 引文斯高帕斯（Scopus）

摘要

The epo genes of many teleosts, including zebrafish, have been cloned following the first identification of nonmammalian EPO from fugu in 2004. The zebrafish (Danio rerio) animal model is well suited for both developmental and genetic analyses for studying vertebrate erythropoiesis. The purpose of this review is to provide an update of recent progress in research on teleost EPO with a focus on its structure, expression and secretion. The EPO receptor and the downstream JAK/STAT signaling pathway are also discussed.

原文	英語
頁（從 - 到）	3545-3552
頁數	8
期刊	Cellular and Molecular Life Sciences
卷	65
發行號	22
DOIs	https://doi.org/10.1007/s00018-008-8231-y
出版狀態	已發佈 - 十一月 2008

ASJC Scopus subject areas

細胞生物學
分子生物學
分子醫學
細胞與分子神經科學
藥理

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10.1007/s00018-008-8231-y

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title = "Erythropoietins from teleosts",

abstract = "The epo genes of many teleosts, including zebrafish, have been cloned following the first identification of nonmammalian EPO from fugu in 2004. The zebrafish (Danio rerio) animal model is well suited for both developmental and genetic analyses for studying vertebrate erythropoiesis. The purpose of this review is to provide an update of recent progress in research on teleost EPO with a focus on its structure, expression and secretion. The EPO receptor and the downstream JAK/STAT signaling pathway are also discussed.",

keywords = "EPO, EPO receptor, Glycosylation, Secretion, Zebrafish",

author = "Chu, {C. Y.} and Cheng, {C. H.} and Yang, {C. H.} and Huang, {C. J.}",

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AU - Yang, C. H.

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AB - The epo genes of many teleosts, including zebrafish, have been cloned following the first identification of nonmammalian EPO from fugu in 2004. The zebrafish (Danio rerio) animal model is well suited for both developmental and genetic analyses for studying vertebrate erythropoiesis. The purpose of this review is to provide an update of recent progress in research on teleost EPO with a focus on its structure, expression and secretion. The EPO receptor and the downstream JAK/STAT signaling pathway are also discussed.

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KW - EPO receptor

KW - Glycosylation

KW - Secretion

KW - Zebrafish

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Erythropoietins from teleosts

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