Trypsin dissection of epithelium from mesenchyme of salivary gland rudiments allows reassembly of glands having either epithelium or mesenchyme selectively marked by T6 chromosomes. Virus-induced tumors in such glands invariably bear the karyotype of the epithelial component. The method solves a specific example from a group of classical problems concerning epithelial as opposed to mesenchymal origin of neoplasms.
|頁（從 - 到）||394-397|
|出版狀態||已發佈 - 一月 1 1971|
ASJC Scopus subject areas
Dawe, C. J., Whang-Peng, J., Morgan, W. D., Hearon, E. C., & Knutsen, T. (1971). Epithelial origin of polyoma salivary tumors in mice: Evidence based on chromosome-marked cells. Science, 171(3969), 394-397.