Eosinophilic meningitis caused by Angiostrongylus cantonensis associated with eating raw snails: Correlation of brain magnetic resonance imaging scans with clinical findings

Hung Chin Tsai, Yung Ching Liu, Calvin M. Kunin, Ping Hong Lai, Susan Shin Jung Lee, Yao Shen Chen, Shue Ren Wann, Wei Ru Lin, Chun Kai Huang, Luo Ping Ger, Hsi Hsun Lin, Muh Yong Yen

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68 引文 斯高帕斯(Scopus)

摘要

Angiostrongylus cantonensis is the most common cause of eosinophilic meningitis worldwide. Human infection occurs after ingestion of the worms in raw snails or fish that serve as intermediate hosts. Two outbreaks of central nervous system infection with A. cantonensis occurred in Kaoshiung, Taiwan, during 1998 and 1999 among Thai laborers who ate raw snails. A detailed clinical studies of 17 of these patients was conducted, including study of 13 patients who underwent magnetic resonance imaging (MRI) scans of the brain. The MRI scans revealed high signal intensities over the globus pallidus and cerebral peduncle on TI-weighted imaging, leptomeningeal enhancement, ventriculomegaly, and punctate areas of abnormal enhancement within the cerebral and cerebellar hemisphere on gadolinium-enhancing T1 imaging, and a hyperintense signal on T2-weighted images. There was a significant correlation between severity of headache, cerebrospinal fluid (CSF) pleocytosis, and CSF and blood eosinophilia with MRI signal intensity in T1-weighted imaging (P <0.05). Eosinophilic meningitis produced by A. cantonensis needs to added to the list of causes of hyperintense basal ganglia lesions found on T1-weighted MRI scans in tropical countries.

原文英語
頁(從 - 到)281-285
頁數5
期刊American Journal of Tropical Medicine and Hygiene
68
發行號3
出版狀態已發佈 - 3月 2003
對外發佈

ASJC Scopus subject areas

  • 寄生物學
  • 傳染性疾病

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