Eosinophilic Gastroenteritis: 10 Years Experience

Chuan‐Mo ‐M Lee, Chi‐Sin ‐S Changehien, Pang‐Chi ‐C Chen, Deng‐Yn ‐Y Lin, I‐Shyan ‐S Sheen, Chia‐Siu ‐S Wang, Dar‐In ‐I Tai, Shyr‐Ming ‐M Sheen‐Chen, Wei‐Jen ‐J Chen, Cheng‐Shyong ‐S Wu

研究成果: 雜誌貢獻文章同行評審

195 引文 斯高帕斯(Scopus)

摘要

Eight patients (five men, three women), mean age 36.9 ± 13.5 (17‐60) yr, were diagnosed to have eosinophilic gastroenteritis. The condition was proved in five patients by biopsies through endoscope, and in three, by operation. All had hypereosinophilia (absolute eosinophil count of 1,337‐21,787/cm3). According to Klein classification, two had mucosal disease, three had muscle layer disease, and three, subserosal disease. The most common symptoms were abdominal pain (100%), diarrhea (62.5%), vomiting (62.5%). and nausea (50%). Four patients (50%) had symptoms for more than 1 yr before diagnosis. Barium studies revealed mucosal edema and/or thickening of the small intestinal wall in three eases (including one case with ulceration), partial gastric outlet obstruction in one case, and narrowing of lumen of the terminal ileum in one case. Hypotonic duodenogram revealed double contour in one case. Ultrasound examination revealed thickening of the intestinal wall in two cases; computer tomography revealed thickening of the intestinal wall in one case. All patients were treated with steroid (40 mg/day for initial dose and relapse; 5–10 mg/day for maintenance). The symptoms subsided and the eosinophil counts returned to normal within 2 wk in seven patients and 1 month in one. Of six patients being followed up for 2–10 yr, one had remission, four needed small maintenance dose of steroid, and one suffered from relapse with intestinal perforation.

原文英語
頁(從 - 到)70-74
頁數5
期刊The American Journal of Gastroenterology
88
發行號1
DOIs
出版狀態已發佈 - 一月 1993
對外發佈

ASJC Scopus subject areas

  • 肝病
  • 消化內科

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