Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants

Shu Fen Chu, Min Tsan Huang, Keng Liang Ou, Erwan Sugiatno, Han Yi Cheng, Yen Heng Huang, Wen Ta Chiu, Tsan Hon Liou

研究成果: 雜誌貢獻文章

7 引文 (Scopus)

摘要

The present study analyzed features of titanium surface modification using laser treatments (denoted as L50-Ti), evaluated its effects on the responses of MG-63 cells, and compared them to polished surfaces (P-Ti) and sandblasted and acid-etched surfaces (SLA-Ti). The P-Ti, SLA-Ti, and L50-Ti surfaces were examined by scanning electron microscopy and X-ray photoelectron spectroscopy. MG63 osteoblast-like cells were seeded on these surfaces, and cell adhesion, proliferation, and morphology were examined. Cell differentiation markers and local factors were also evaluated. The P-Ti surface presented parallel grooves with a smoother surface roughness. The SLA-Ti surface exhibited irregular peaks and valleys with hydrophobic properties, whereas the L50-Ti surface presented micro-/nanoporous structures with hydrophilic properties. Cell adhesion, proliferation, differentiation, and the production of prostaglandin E2 were greater on L50-Ti surfaces than those on P-Ti and SLA-Ti surfaces. Laser treatment can fabricate micro-/nanoporous Ti surfaces with hydrophilic properties, and these surface characteristics enhanced the responses of MG-63 cells.
原文英語
頁(從 - 到)726-732
頁數7
期刊Journal of Alloys and Compounds
684
DOIs
出版狀態已發佈 - 十一月 5 2016

指紋

Scaffolds
Cell adhesion
Lasers
Differentiation Antigens
Osteoblasts
Titanium
Dinoprostone
Surface treatment
X ray photoelectron spectroscopy
Surface roughness
Microstructure
Scanning electron microscopy
Acids

ASJC Scopus subject areas

  • Mechanical Engineering
  • Mechanics of Materials
  • Materials Chemistry
  • Metals and Alloys

引用此文

Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants. / Chu, Shu Fen; Huang, Min Tsan; Ou, Keng Liang; Sugiatno, Erwan; Cheng, Han Yi; Huang, Yen Heng; Chiu, Wen Ta; Liou, Tsan Hon.

於: Journal of Alloys and Compounds, 卷 684, 05.11.2016, p. 726-732.

研究成果: 雜誌貢獻文章

Chu, Shu Fen ; Huang, Min Tsan ; Ou, Keng Liang ; Sugiatno, Erwan ; Cheng, Han Yi ; Huang, Yen Heng ; Chiu, Wen Ta ; Liou, Tsan Hon. / Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants. 於: Journal of Alloys and Compounds. 2016 ; 卷 684. 頁 726-732.
@article{62507b4b88fa4ef28d2157c96500518c,
title = "Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants",
abstract = "The present study analyzed features of titanium surface modification using laser treatments (denoted as L50-Ti), evaluated its effects on the responses of MG-63 cells, and compared them to polished surfaces (P-Ti) and sandblasted and acid-etched surfaces (SLA-Ti). The P-Ti, SLA-Ti, and L50-Ti surfaces were examined by scanning electron microscopy and X-ray photoelectron spectroscopy. MG63 osteoblast-like cells were seeded on these surfaces, and cell adhesion, proliferation, and morphology were examined. Cell differentiation markers and local factors were also evaluated. The P-Ti surface presented parallel grooves with a smoother surface roughness. The SLA-Ti surface exhibited irregular peaks and valleys with hydrophobic properties, whereas the L50-Ti surface presented micro-/nanoporous structures with hydrophilic properties. Cell adhesion, proliferation, differentiation, and the production of prostaglandin E2 were greater on L50-Ti surfaces than those on P-Ti and SLA-Ti surfaces. Laser treatment can fabricate micro-/nanoporous Ti surfaces with hydrophilic properties, and these surface characteristics enhanced the responses of MG-63 cells.",
keywords = "Laser treatment, Micro-/nanoporous structures, Prostaglandin E",
author = "Chu, {Shu Fen} and Huang, {Min Tsan} and Ou, {Keng Liang} and Erwan Sugiatno and Cheng, {Han Yi} and Huang, {Yen Heng} and Chiu, {Wen Ta} and Liou, {Tsan Hon}",
year = "2016",
month = "11",
day = "5",
doi = "10.1016/j.jallcom.2016.05.134",
language = "English",
volume = "684",
pages = "726--732",
journal = "Journal of Alloys and Compounds",
issn = "0925-8388",
publisher = "Elsevier",

}

TY - JOUR

T1 - Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants

AU - Chu, Shu Fen

AU - Huang, Min Tsan

AU - Ou, Keng Liang

AU - Sugiatno, Erwan

AU - Cheng, Han Yi

AU - Huang, Yen Heng

AU - Chiu, Wen Ta

AU - Liou, Tsan Hon

PY - 2016/11/5

Y1 - 2016/11/5

N2 - The present study analyzed features of titanium surface modification using laser treatments (denoted as L50-Ti), evaluated its effects on the responses of MG-63 cells, and compared them to polished surfaces (P-Ti) and sandblasted and acid-etched surfaces (SLA-Ti). The P-Ti, SLA-Ti, and L50-Ti surfaces were examined by scanning electron microscopy and X-ray photoelectron spectroscopy. MG63 osteoblast-like cells were seeded on these surfaces, and cell adhesion, proliferation, and morphology were examined. Cell differentiation markers and local factors were also evaluated. The P-Ti surface presented parallel grooves with a smoother surface roughness. The SLA-Ti surface exhibited irregular peaks and valleys with hydrophobic properties, whereas the L50-Ti surface presented micro-/nanoporous structures with hydrophilic properties. Cell adhesion, proliferation, differentiation, and the production of prostaglandin E2 were greater on L50-Ti surfaces than those on P-Ti and SLA-Ti surfaces. Laser treatment can fabricate micro-/nanoporous Ti surfaces with hydrophilic properties, and these surface characteristics enhanced the responses of MG-63 cells.

AB - The present study analyzed features of titanium surface modification using laser treatments (denoted as L50-Ti), evaluated its effects on the responses of MG-63 cells, and compared them to polished surfaces (P-Ti) and sandblasted and acid-etched surfaces (SLA-Ti). The P-Ti, SLA-Ti, and L50-Ti surfaces were examined by scanning electron microscopy and X-ray photoelectron spectroscopy. MG63 osteoblast-like cells were seeded on these surfaces, and cell adhesion, proliferation, and morphology were examined. Cell differentiation markers and local factors were also evaluated. The P-Ti surface presented parallel grooves with a smoother surface roughness. The SLA-Ti surface exhibited irregular peaks and valleys with hydrophobic properties, whereas the L50-Ti surface presented micro-/nanoporous structures with hydrophilic properties. Cell adhesion, proliferation, differentiation, and the production of prostaglandin E2 were greater on L50-Ti surfaces than those on P-Ti and SLA-Ti surfaces. Laser treatment can fabricate micro-/nanoporous Ti surfaces with hydrophilic properties, and these surface characteristics enhanced the responses of MG-63 cells.

KW - Laser treatment

KW - Micro-/nanoporous structures

KW - Prostaglandin E

UR - http://www.scopus.com/inward/record.url?scp=84974578063&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84974578063&partnerID=8YFLogxK

U2 - 10.1016/j.jallcom.2016.05.134

DO - 10.1016/j.jallcom.2016.05.134

M3 - Article

AN - SCOPUS:84974578063

VL - 684

SP - 726

EP - 732

JO - Journal of Alloys and Compounds

JF - Journal of Alloys and Compounds

SN - 0925-8388

ER -