Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants

Shu Fen Chu, Min Tsan Huang, Keng Liang Ou, Erwan Sugiatno, Han Yi Cheng, Yen Heng Huang, Wen Ta Chiu, Tsan Hon Liou

研究成果: 雜誌貢獻文章同行評審

8 引文 斯高帕斯(Scopus)

摘要

The present study analyzed features of titanium surface modification using laser treatments (denoted as L50-Ti), evaluated its effects on the responses of MG-63 cells, and compared them to polished surfaces (P-Ti) and sandblasted and acid-etched surfaces (SLA-Ti). The P-Ti, SLA-Ti, and L50-Ti surfaces were examined by scanning electron microscopy and X-ray photoelectron spectroscopy. MG63 osteoblast-like cells were seeded on these surfaces, and cell adhesion, proliferation, and morphology were examined. Cell differentiation markers and local factors were also evaluated. The P-Ti surface presented parallel grooves with a smoother surface roughness. The SLA-Ti surface exhibited irregular peaks and valleys with hydrophobic properties, whereas the L50-Ti surface presented micro-/nanoporous structures with hydrophilic properties. Cell adhesion, proliferation, differentiation, and the production of prostaglandin E2 were greater on L50-Ti surfaces than those on P-Ti and SLA-Ti surfaces. Laser treatment can fabricate micro-/nanoporous Ti surfaces with hydrophilic properties, and these surface characteristics enhanced the responses of MG-63 cells.
原文英語
頁(從 - 到)726-732
頁數7
期刊Journal of Alloys and Compounds
684
DOIs
出版狀態已發佈 - 十一月 5 2016

ASJC Scopus subject areas

  • Mechanical Engineering
  • Mechanics of Materials
  • Materials Chemistry
  • Metals and Alloys

指紋 深入研究「Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants」主題。共同形成了獨特的指紋。

引用此