Endoscopic nasopharyngectomy with potassium-titanyl-phosphate (KTP) laser for early locally recurrent nasopharyngeal carcinoma

Jenq Yuh Ko, Cheng Ping Wang, Lai Lei Ting, Tsung Lin Yang, Ching Ting Tan

研究成果: 雜誌貢獻文章

33 引文 (Scopus)

摘要

Background. Although early recurrent nasopharyngeal carcinoma (NPC) can be treated with surgery alone, conventional nasopharyngectomy still results in serious complications. Endoscopic nasopharyngectomy has been introduced, but data on the treatment outcomes of this technique are lacking. Methods. From March 2004 to December 2007, 28 patients with rT1 or rT2a NPC underwent potassium-titanyl-phosphate (KTP) laser nasopharyngectomy by endoscopic techniques with curative intent. Results. Twenty-five patients underwent surgery alone. Only 3 patients received postoperative adjuvant therapy. The 2-year local disease-free and 2-year overall survival rates for the 12 patients with rT1 tumor and for the 16 patients with rT2a tumor were 100% and 41.7% (p = .007); and 90.9% and 38.5% (p = .03), respectively. Only 3 patients had obvious osteonecrosis at the nasopharynx, and 1 patient developed hypoglossal nerve dysfuction. Conclusions. Endoscopic KTP laser nasopharyngectomy is a simple, safe, and successful procedure for treating rT1 NPC, though its benefits are less clear for rT2a.

原文英語
頁(從 - 到)1309-1315
頁數7
期刊Head and Neck
31
發行號10
DOIs
出版狀態已發佈 - 十月 1 2009
對外發佈Yes

指紋

Solid-State Lasers
Hypoglossal Nerve
Osteonecrosis
Nasopharynx
Nasopharyngeal carcinoma
Neoplasms
Survival Rate

ASJC Scopus subject areas

  • Otorhinolaryngology

引用此文

Endoscopic nasopharyngectomy with potassium-titanyl-phosphate (KTP) laser for early locally recurrent nasopharyngeal carcinoma. / Ko, Jenq Yuh; Wang, Cheng Ping; Ting, Lai Lei; Yang, Tsung Lin; Tan, Ching Ting.

於: Head and Neck, 卷 31, 編號 10, 01.10.2009, p. 1309-1315.

研究成果: 雜誌貢獻文章

Ko, Jenq Yuh ; Wang, Cheng Ping ; Ting, Lai Lei ; Yang, Tsung Lin ; Tan, Ching Ting. / Endoscopic nasopharyngectomy with potassium-titanyl-phosphate (KTP) laser for early locally recurrent nasopharyngeal carcinoma. 於: Head and Neck. 2009 ; 卷 31, 編號 10. 頁 1309-1315.
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abstract = "Background. Although early recurrent nasopharyngeal carcinoma (NPC) can be treated with surgery alone, conventional nasopharyngectomy still results in serious complications. Endoscopic nasopharyngectomy has been introduced, but data on the treatment outcomes of this technique are lacking. Methods. From March 2004 to December 2007, 28 patients with rT1 or rT2a NPC underwent potassium-titanyl-phosphate (KTP) laser nasopharyngectomy by endoscopic techniques with curative intent. Results. Twenty-five patients underwent surgery alone. Only 3 patients received postoperative adjuvant therapy. The 2-year local disease-free and 2-year overall survival rates for the 12 patients with rT1 tumor and for the 16 patients with rT2a tumor were 100{\%} and 41.7{\%} (p = .007); and 90.9{\%} and 38.5{\%} (p = .03), respectively. Only 3 patients had obvious osteonecrosis at the nasopharynx, and 1 patient developed hypoglossal nerve dysfuction. Conclusions. Endoscopic KTP laser nasopharyngectomy is a simple, safe, and successful procedure for treating rT1 NPC, though its benefits are less clear for rT2a.",
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AU - Yang, Tsung Lin

AU - Tan, Ching Ting

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N2 - Background. Although early recurrent nasopharyngeal carcinoma (NPC) can be treated with surgery alone, conventional nasopharyngectomy still results in serious complications. Endoscopic nasopharyngectomy has been introduced, but data on the treatment outcomes of this technique are lacking. Methods. From March 2004 to December 2007, 28 patients with rT1 or rT2a NPC underwent potassium-titanyl-phosphate (KTP) laser nasopharyngectomy by endoscopic techniques with curative intent. Results. Twenty-five patients underwent surgery alone. Only 3 patients received postoperative adjuvant therapy. The 2-year local disease-free and 2-year overall survival rates for the 12 patients with rT1 tumor and for the 16 patients with rT2a tumor were 100% and 41.7% (p = .007); and 90.9% and 38.5% (p = .03), respectively. Only 3 patients had obvious osteonecrosis at the nasopharynx, and 1 patient developed hypoglossal nerve dysfuction. Conclusions. Endoscopic KTP laser nasopharyngectomy is a simple, safe, and successful procedure for treating rT1 NPC, though its benefits are less clear for rT2a.

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