22 引文 斯高帕斯(Scopus)

摘要

Dioscorin, the tuber storage protein of yam, was reported to have immunomodulatory activity in RAW264.7 murine macrophage cell lines (Food and Chemical Toxicology, 2007, 45, 2312-2318). However, the immunomodulatory function of dioscorin after being ingested was not elucidated in vivo. Hence, BALB/c mice were given oral dioscorin (2.5 and 20 mg/kg/day) once a day for 21-days. Lymphocyte subpopulation changes in the peripheral blood and splenocytes, stimulation in phagocytosis of the polymorphonuclear cell (PMN) and monocytes, the natural killer (NK) cell cytotoxicity, the splenocyte proliferation, and cytokine secretions in the presence of PHA were determined. The number changes of Peyer's patches and secreted IgA (slgA) in the feces were determined. Oral dioscorin for 21-days increased the subpopulation in natural killer cells (CD49+) and/or B cells (CD19+), elevated the phagocytosis of PMN (p

原文英語
頁(從 - 到)9274-9279
頁數6
期刊Journal of Agricultural and Food Chemistry
57
發行號19
DOIs
出版狀態已發佈 - 2009

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Chemistry(all)

指紋 深入研究「Effects of oral administration of Yam tuber storage protein, dioscorin, to BALB/c mice for 21-days on immune responses」主題。共同形成了獨特的指紋。

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