Effects of cold exposure on autonomic changes during the last rapid eye movement sleep transition and morning blood pressure surge in humans

Terry B.J. Kuo, Cian Hui Hong, I. Te Hsieh, Guo She Lee, Cheryl C.H. Yang

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

摘要

Background: Various studies have linked the occurrence of cardiovascular events and low ambient temperatures as well as the morning blood pressure surge (MBPS). We hypothesized that low ambient temperatures produce a higher sympathetic change during the last rapid eye movement (REM) sleep transition and that this may play an important role in cold-related cardiovascular events. Methods: All experiments were carried out on 12 healthy male adults, aged 24.00. ±. 0.74. years, who participated in two experimental conditions randomly (<1. day apart): warm (23. °C) and cold (16. °C). Blood pressure (BP) was measured every 30. min for 24. h by autonomic ambulatory BP monitoring. The electroencephalograms, electrocardiograms, ambient temperature, near-body temperature, and physical activity were recorded by miniature polysomnography for 24. h. Results: The cold conditions resulted in: (i) higher MBPS than under warm conditions; (ii) significant and greater sympathetic index changes during the sleep-wake transition than during cover-to-uncover and supine-to-sit position tests; (iii) the non-REM-REM transition-related sympathetic elevation during the cold conditions being significantly higher in late sleep period than in early sleep period; (iv) at 1. h prior to morning awakening, the value of total power of heart rate variability changes being significantly negatively correlated with the changes of near-body temperature; and (v) significantly higher arousal index and shorter average interval of REM periods than in warm conditions. Conclusion: Cold exposure elevates the amplitude of MBPS and is associated with late sleep stage transition sympathetic activation, which might have important implications for cold-related cardiovascular events.
原文英語
頁(從 - 到)986-997
頁數12
期刊Sleep Medicine
15
發行號8
DOIs
出版狀態已發佈 - 2014
對外發佈Yes

ASJC Scopus subject areas

  • Medicine(all)

指紋 深入研究「Effects of cold exposure on autonomic changes during the last rapid eye movement sleep transition and morning blood pressure surge in humans」主題。共同形成了獨特的指紋。

  • 引用此