Modification of the cantharidinimide structure led to the discovery of a novel class of antitumor compounds. These cantharidinimide derivatives containing aliphartic, aryl, and pyridyl groups showed some effect in vitro against HepG2 and HL-60 cells.
ASJC Scopus subject areas
- Organic Chemistry
- Drug Discovery
Lin, L. H., Huang, H. S., Lin, C. C., Lee, L. W., & Lin, P. Y. (2004). Effects of cantharidinimides on human carcinoma cells. Chemical and Pharmaceutical Bulletin, 52(7), 855-857. https://doi.org/10.1248/cpb.52.855