Effects of breathing frequency on baroreflex effectiveness index and spontaneous baroreflex sensitivity derived by sequence analysis

Yong Ping Wang, Terry B.J. Kuo, Chun Ting Lai, Guo She Lee, Cheryl C.H. Yang

研究成果: 雜誌貢獻文章

7 引文 (Scopus)

摘要

AIMS: High-frequency paced breathing is required to avoid overestimation when measuring spectral baroreflex sensitivity (BRSLF) to predict outcomes in cardiovascular patients. We examined whether respiration should also be controlled when measuring the baroreflex effectiveness index (BEI) and baroreflex sensitivity (BRSseq), which are derived by sequence analysis. METHODS: We studied 17 healthy young adults who breathed spontaneously and controlled their breathing to rates of 0.1, 0.2, 0.3 and 0.4 Hz in the supine position. We found respiratory influences on BEI and BRSseq depended on the lag used to pair the systolic arterial pressure and R-R interval in a sequence. Therefore, the two baroreflex measures were obtained by selecting the lag with a larger number of sequences for each section. RESULTS: BEI decreased progressively as the breathing frequency increased. BRSseq remained unchanged at rates of 0.1, 0.2 and 0.3 Hz, but was reduced during 0.4 Hz breathing. In contrast, BRSLF was constant during 0.2, 0.3, and 0.4 Hz breathing, but was greater at 0.1 Hz. Rates of spontaneous breathing range from 0.1 to 0.32 Hz with a mean value of 0.19 Hz. Baroreflex measures obtained for spontaneous breathing were found to be between the values for 0.1 and 0.3 Hz paced breathing. CONCLUSION: BEI and BRSseq do not remain constant at various breathing frequencies. Nonetheless, considering the pattern of change and the frequency range of spontaneous respiration, the authors suggest that high-frequency paced breathing is not necessary when measuring the BEI and BRSseq under the conditions used in this study.
原文英語
頁(從 - 到)2151-2158
頁數8
期刊Journal of Hypertension
30
發行號11
DOIs
出版狀態已發佈 - 十一月 2012
對外發佈Yes

指紋

Baroreflex
Sequence Analysis
Respiration
Supine Position
Young Adult
Arterial Pressure

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

引用此文

Effects of breathing frequency on baroreflex effectiveness index and spontaneous baroreflex sensitivity derived by sequence analysis. / Wang, Yong Ping; Kuo, Terry B.J.; Lai, Chun Ting; Lee, Guo She; Yang, Cheryl C.H.

於: Journal of Hypertension, 卷 30, 編號 11, 11.2012, p. 2151-2158.

研究成果: 雜誌貢獻文章

Wang, Yong Ping ; Kuo, Terry B.J. ; Lai, Chun Ting ; Lee, Guo She ; Yang, Cheryl C.H. / Effects of breathing frequency on baroreflex effectiveness index and spontaneous baroreflex sensitivity derived by sequence analysis. 於: Journal of Hypertension. 2012 ; 卷 30, 編號 11. 頁 2151-2158.
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abstract = "AIMS: High-frequency paced breathing is required to avoid overestimation when measuring spectral baroreflex sensitivity (BRSLF) to predict outcomes in cardiovascular patients. We examined whether respiration should also be controlled when measuring the baroreflex effectiveness index (BEI) and baroreflex sensitivity (BRSseq), which are derived by sequence analysis. METHODS: We studied 17 healthy young adults who breathed spontaneously and controlled their breathing to rates of 0.1, 0.2, 0.3 and 0.4 Hz in the supine position. We found respiratory influences on BEI and BRSseq depended on the lag used to pair the systolic arterial pressure and R-R interval in a sequence. Therefore, the two baroreflex measures were obtained by selecting the lag with a larger number of sequences for each section. RESULTS: BEI decreased progressively as the breathing frequency increased. BRSseq remained unchanged at rates of 0.1, 0.2 and 0.3 Hz, but was reduced during 0.4 Hz breathing. In contrast, BRSLF was constant during 0.2, 0.3, and 0.4 Hz breathing, but was greater at 0.1 Hz. Rates of spontaneous breathing range from 0.1 to 0.32 Hz with a mean value of 0.19 Hz. Baroreflex measures obtained for spontaneous breathing were found to be between the values for 0.1 and 0.3 Hz paced breathing. CONCLUSION: BEI and BRSseq do not remain constant at various breathing frequencies. Nonetheless, considering the pattern of change and the frequency range of spontaneous respiration, the authors suggest that high-frequency paced breathing is not necessary when measuring the BEI and BRSseq under the conditions used in this study.",
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AU - Yang, Cheryl C.H.

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N2 - AIMS: High-frequency paced breathing is required to avoid overestimation when measuring spectral baroreflex sensitivity (BRSLF) to predict outcomes in cardiovascular patients. We examined whether respiration should also be controlled when measuring the baroreflex effectiveness index (BEI) and baroreflex sensitivity (BRSseq), which are derived by sequence analysis. METHODS: We studied 17 healthy young adults who breathed spontaneously and controlled their breathing to rates of 0.1, 0.2, 0.3 and 0.4 Hz in the supine position. We found respiratory influences on BEI and BRSseq depended on the lag used to pair the systolic arterial pressure and R-R interval in a sequence. Therefore, the two baroreflex measures were obtained by selecting the lag with a larger number of sequences for each section. RESULTS: BEI decreased progressively as the breathing frequency increased. BRSseq remained unchanged at rates of 0.1, 0.2 and 0.3 Hz, but was reduced during 0.4 Hz breathing. In contrast, BRSLF was constant during 0.2, 0.3, and 0.4 Hz breathing, but was greater at 0.1 Hz. Rates of spontaneous breathing range from 0.1 to 0.32 Hz with a mean value of 0.19 Hz. Baroreflex measures obtained for spontaneous breathing were found to be between the values for 0.1 and 0.3 Hz paced breathing. CONCLUSION: BEI and BRSseq do not remain constant at various breathing frequencies. Nonetheless, considering the pattern of change and the frequency range of spontaneous respiration, the authors suggest that high-frequency paced breathing is not necessary when measuring the BEI and BRSseq under the conditions used in this study.

AB - AIMS: High-frequency paced breathing is required to avoid overestimation when measuring spectral baroreflex sensitivity (BRSLF) to predict outcomes in cardiovascular patients. We examined whether respiration should also be controlled when measuring the baroreflex effectiveness index (BEI) and baroreflex sensitivity (BRSseq), which are derived by sequence analysis. METHODS: We studied 17 healthy young adults who breathed spontaneously and controlled their breathing to rates of 0.1, 0.2, 0.3 and 0.4 Hz in the supine position. We found respiratory influences on BEI and BRSseq depended on the lag used to pair the systolic arterial pressure and R-R interval in a sequence. Therefore, the two baroreflex measures were obtained by selecting the lag with a larger number of sequences for each section. RESULTS: BEI decreased progressively as the breathing frequency increased. BRSseq remained unchanged at rates of 0.1, 0.2 and 0.3 Hz, but was reduced during 0.4 Hz breathing. In contrast, BRSLF was constant during 0.2, 0.3, and 0.4 Hz breathing, but was greater at 0.1 Hz. Rates of spontaneous breathing range from 0.1 to 0.32 Hz with a mean value of 0.19 Hz. Baroreflex measures obtained for spontaneous breathing were found to be between the values for 0.1 and 0.3 Hz paced breathing. CONCLUSION: BEI and BRSseq do not remain constant at various breathing frequencies. Nonetheless, considering the pattern of change and the frequency range of spontaneous respiration, the authors suggest that high-frequency paced breathing is not necessary when measuring the BEI and BRSseq under the conditions used in this study.

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