Effect of proteoglycans on the differentiation of ATDC5 cells to chondrocytes

研究成果: 書貢獻/報告類型會議貢獻

摘要

The effect of intact proteoglycan as a material for supporting the cell growth and tissue regeneration was discussed. The efficacy of proteoglycan on the regulation of cell proliferation and differentiation was evaluated by introducing the intact proteoglycan instead of using the GAG or core protein alone in an in vitro cultural system. The results indicated that proteoglycans could induce the differentiation of ATDC5 cells to chondrocytes. It was found that both heparan sulfate proteoglycan (CS/DSPG) could enhance the induced differentiation of ATDC5 cells to chondrocytes by insulin. The dual effect of proteoglycan showed its potential to be used in a newly developed bio-mimic material for cartilage repair and regeneration.
原文英語
主出版物標題Transactions - 7th World Biomaterials Congress
頁面1009
頁數1
出版狀態已發佈 - 2004
事件Transactions - 7th World Biomaterials Congress - Sydney, 澳大利亚
持續時間: 五月 17 2004五月 21 2004

其他

其他Transactions - 7th World Biomaterials Congress
國家澳大利亚
城市Sydney
期間5/17/045/21/04

指紋

Tissue regeneration
Insulin
Cell proliferation
Cartilage
Cell growth
Proteoglycans
Repair
Proteins
Sulfates

ASJC Scopus subject areas

  • Engineering(all)

引用此文

Yang, W. C. V., & Chang, S. C. (2004). Effect of proteoglycans on the differentiation of ATDC5 cells to chondrocytes. 於 Transactions - 7th World Biomaterials Congress (頁 1009)

Effect of proteoglycans on the differentiation of ATDC5 cells to chondrocytes. / Yang, W. C V; Chang, S. C.

Transactions - 7th World Biomaterials Congress. 2004. p. 1009.

研究成果: 書貢獻/報告類型會議貢獻

Yang, WCV & Chang, SC 2004, Effect of proteoglycans on the differentiation of ATDC5 cells to chondrocytes. 於 Transactions - 7th World Biomaterials Congress. 頁 1009, Transactions - 7th World Biomaterials Congress, Sydney, 澳大利亚, 5/17/04.
Yang WCV, Chang SC. Effect of proteoglycans on the differentiation of ATDC5 cells to chondrocytes. 於 Transactions - 7th World Biomaterials Congress. 2004. p. 1009
@inproceedings{e304a61843c84f808ed318f103b9430d,
title = "Effect of proteoglycans on the differentiation of ATDC5 cells to chondrocytes",
abstract = "The effect of intact proteoglycan as a material for supporting the cell growth and tissue regeneration was discussed. The efficacy of proteoglycan on the regulation of cell proliferation and differentiation was evaluated by introducing the intact proteoglycan instead of using the GAG or core protein alone in an in vitro cultural system. The results indicated that proteoglycans could induce the differentiation of ATDC5 cells to chondrocytes. It was found that both heparan sulfate proteoglycan (CS/DSPG) could enhance the induced differentiation of ATDC5 cells to chondrocytes by insulin. The dual effect of proteoglycan showed its potential to be used in a newly developed bio-mimic material for cartilage repair and regeneration.",
author = "Yang, {W. C V} and Chang, {S. C.}",
year = "2004",
language = "English",
isbn = "1877040193",
pages = "1009",
booktitle = "Transactions - 7th World Biomaterials Congress",

}

TY - GEN

T1 - Effect of proteoglycans on the differentiation of ATDC5 cells to chondrocytes

AU - Yang, W. C V

AU - Chang, S. C.

PY - 2004

Y1 - 2004

N2 - The effect of intact proteoglycan as a material for supporting the cell growth and tissue regeneration was discussed. The efficacy of proteoglycan on the regulation of cell proliferation and differentiation was evaluated by introducing the intact proteoglycan instead of using the GAG or core protein alone in an in vitro cultural system. The results indicated that proteoglycans could induce the differentiation of ATDC5 cells to chondrocytes. It was found that both heparan sulfate proteoglycan (CS/DSPG) could enhance the induced differentiation of ATDC5 cells to chondrocytes by insulin. The dual effect of proteoglycan showed its potential to be used in a newly developed bio-mimic material for cartilage repair and regeneration.

AB - The effect of intact proteoglycan as a material for supporting the cell growth and tissue regeneration was discussed. The efficacy of proteoglycan on the regulation of cell proliferation and differentiation was evaluated by introducing the intact proteoglycan instead of using the GAG or core protein alone in an in vitro cultural system. The results indicated that proteoglycans could induce the differentiation of ATDC5 cells to chondrocytes. It was found that both heparan sulfate proteoglycan (CS/DSPG) could enhance the induced differentiation of ATDC5 cells to chondrocytes by insulin. The dual effect of proteoglycan showed its potential to be used in a newly developed bio-mimic material for cartilage repair and regeneration.

UR - http://www.scopus.com/inward/record.url?scp=13844256614&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13844256614&partnerID=8YFLogxK

M3 - Conference contribution

SN - 1877040193

SN - 9781877040191

SP - 1009

BT - Transactions - 7th World Biomaterials Congress

ER -