Effect of prolonged radiation exposure on the thyroid gland of residents living in 60Co-contaminated rebar buildings

Tien Chun Chang, Wei Li Chen, Wushou P. Chang, Chien Jen Chen

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)


Purpose: To evaluate prolonged low dose-rate γ-exposure effects on the thyroid glands of residents living in 60Co-contaminated steel buildings. Materials and methods: Physical examination and ultrasonography of the thyroid, determination of thyroid function and anti-thyroid microsomal antibodies were performed for 1346 residents. Ultrasound-guided aspiration cytology was done for thyroid nodules. The study subjects were stratified by age at examination (≤ 15 and > 15 years), sex and exposure dose to the body. Dose-response data on the prevalence of various thyroid diseases were analysed by the multiple logistic regression analysis. Results and conclusions: The prevalence of simple goitre was related to the exposure with a dose-response relationship for males of all ages, and for females of ≤15 years. There was a biological gradient of thyroid cyst prevalence with the increase in exposure dose for females of all ages. The prevalence of elevated serum tri-iodothyronine level showed a dose-response relationship for males of ≤15 years. A significant increase in thyroid abnormalities with dose was observed for males of all ages, and for females of ≤ 15 years.

頁(從 - 到)1117-1122
期刊International Journal of Radiation Biology
出版狀態已發佈 - 2001


ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Nuclear Energy and Engineering
  • Radiation