Effect of Lactobacillus plantarum TWK10 on improving endurance performance in humans

Wen Ching Huang, Yi Ju Hsu, Huashuai Li, Nai Wen Kan, Yi Ming Chen, Jin Seng Lin, Tien Ken Hsu, Tsung Yu Tsai, Yen Shuo Chiu, Chi Chang Huang

研究成果: 雜誌貢獻文章

7 引文 (Scopus)

摘要

Microbiota is currently an important issue in disease and health and many studies have revealed it to play an important role in physiological homeostasis and health promotion. Lactobacillus plantarum (L. plantarum), isolated from Taiwan pickled vegetables, is a well-known probiotic microorganism. In a recent animal study, it was shown that supplementation of mice with L. plantarum TWK10 (TWK10) could increase muscle mass, improve exercise performance and exert anti-fatigue effects. In order to examine the ergogenic effect of TWK10 supplementation on endurance performance in humans, we conducted a human double-blind placebo-controlled clinical study. A total of sixteen adult subjects over 20 years of age were recruited and randomly allocated to the placebo or TWK10 group (n = 8 each). The TWK10 group received 6 weeks of supplementation. Physiological assessments were conducted by exhaustive treadmill exercise measurements and related biochemical indexes. After 6 weeks of supplementation, levels of lactic acid, blood ammonia, blood glucose, free fatty acid (FFA) and creatine kinase (CK) were evaluated during exhaustive exercise. We were able to show that the TWK10 group had significantly higher endurance performance and glucose content in a maximal treadmill running test compared to the placebo group (P < 0.05), suggesting that TWK10 supplementation may be beneficial to energy harvest. Taken together, our results suggest that TWK10 has the potential to be an aerobic exercise supplement for physiological adaptation or an ergogenic supplement with health benefits for amateur runners.

原文英語
頁(從 - 到)163-170
頁數8
期刊Chinese Journal of Physiology
61
發行號3
DOIs
出版狀態已發佈 - 一月 1 2018

指紋

Lactobacillus plantarum
Exercise
Placebos
Performance-Enhancing Substances
Physiological Adaptation
Microbiota
Probiotics
Insurance Benefits
Creatine Kinase
Health Promotion
Taiwan
Exercise Test
Ammonia
Nonesterified Fatty Acids
Vegetables
Fatigue
Blood Glucose
Lactic Acid
Homeostasis
Glucose

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

引用此文

Effect of Lactobacillus plantarum TWK10 on improving endurance performance in humans. / Huang, Wen Ching; Hsu, Yi Ju; Li, Huashuai; Kan, Nai Wen; Chen, Yi Ming; Lin, Jin Seng; Hsu, Tien Ken; Tsai, Tsung Yu; Chiu, Yen Shuo; Huang, Chi Chang.

於: Chinese Journal of Physiology, 卷 61, 編號 3, 01.01.2018, p. 163-170.

研究成果: 雜誌貢獻文章

Huang, Wen Ching ; Hsu, Yi Ju ; Li, Huashuai ; Kan, Nai Wen ; Chen, Yi Ming ; Lin, Jin Seng ; Hsu, Tien Ken ; Tsai, Tsung Yu ; Chiu, Yen Shuo ; Huang, Chi Chang. / Effect of Lactobacillus plantarum TWK10 on improving endurance performance in humans. 於: Chinese Journal of Physiology. 2018 ; 卷 61, 編號 3. 頁 163-170.
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