Effect of glutaraldehyde on the humoral immunogenicity and structure of porcine dermal collagen membranes

King Jean Wu, Cheng Y. Wang, Hsein K. Lu

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)

摘要

Objectives: Our previous studies showed that the biodegradation rate of cross-linked porcine dermal collagen membrane (PDCM) could be retarded without changing its biocompatible character. The purpose of this study was to assay the humoral immune response of PDCM reconstitute with glutaraldehyde (GA) and observe their surface architectures. Methods: PDCM reconstituted with GA (0, 0.01, 0.05, and 3%) was implanted in 30 Sprague-Dawley rats. Sample sera were collected 3, 6, and 9 weeks after surgery and assayed with ELISA. The architectures of PDCMs were observed under SEM (100×). Results: The study showed that non cross-linked PDCM induced the highest immune response than any other cross-linked PDCMs (by optical density (OD) values, P
原文英語
頁(從 - 到)305-311
頁數7
期刊Archives of Oral Biology
49
發行號4
DOIs
出版狀態已發佈 - 四月 2004

ASJC Scopus subject areas

  • Dentistry(all)

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