Effect of extraperitoneal bupivacaine analgesia in laparoscopic inguinal hernia repair

A meta-analysis of randomized controlled trials

Y. S. Tong, Chien-Chih Wu, Chyi-Huey Bai, H. C. Lee, Hung-Hua Liang, Li-Jen Kuo, Po-Li Wei, Ka-Wai Tam

研究成果: 雜誌貢獻文章

9 引文 (Scopus)

摘要

Background: Laparoscopic total extraperitoneal (TEP) inguinal hernioplasty is significantly less painful than open repair, but it is not completely painless. Local anesthetics are thought to decrease postoperative pain when placed at the surgical site. We conducted a systematic review of randomized controlled trials (RCTs) to evaluate the efficacy of extraperitoneal bupivacaine treatment during laparoscopic inguinal hernia repair for the reduction of postoperative pain. Methods: We conducted a systematic review and meta-analysis of RCTs that investigated the outcomes of extraperitoneal bupivacaine analgesia versus control in laparoscopic TEP hernia repair. Pain was assessed using a visual analog scale at 4-6 h and at 24 h following the surgery. The secondary outcomes included complications and analgesia consumption. Results: We reviewed eight trials that included a total of 373 patients. We found no difference between the groups in postoperative pain reduction following laparoscopic TEP inguinal hernia repair. The intensity of pain was not significantly different between the bupivacaine treatment group and the control group. The pooled mean differences in pain scores were -0.26 (95 % CI -0.72 to 0.21) at 4-6 h and -0.47 (95 % CI -1.24 to 0.29) at 24 h. No bupivacaine-related complications were reported. Conclusion: Extraperitoneal bupivacaine treatment during laparoscopic TEP inguinal hernioplasty is not more efficacious for the reduction of postoperative pain than placebo.
原文英語
頁(從 - 到)177-183
頁數7
期刊Hernia
18
發行號2
DOIs
出版狀態已發佈 - 2014

指紋

Inguinal Hernia
Herniorrhaphy
Bupivacaine
Analgesia
Meta-Analysis
Postoperative Pain
Randomized Controlled Trials
Groin
Pain
Local Anesthetics
Visual Analog Scale
Therapeutics
Placebos
Control Groups

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

引用此文

@article{fdaa0f7ccbe44538872b5ad88e09594a,
title = "Effect of extraperitoneal bupivacaine analgesia in laparoscopic inguinal hernia repair: A meta-analysis of randomized controlled trials",
abstract = "Background: Laparoscopic total extraperitoneal (TEP) inguinal hernioplasty is significantly less painful than open repair, but it is not completely painless. Local anesthetics are thought to decrease postoperative pain when placed at the surgical site. We conducted a systematic review of randomized controlled trials (RCTs) to evaluate the efficacy of extraperitoneal bupivacaine treatment during laparoscopic inguinal hernia repair for the reduction of postoperative pain. Methods: We conducted a systematic review and meta-analysis of RCTs that investigated the outcomes of extraperitoneal bupivacaine analgesia versus control in laparoscopic TEP hernia repair. Pain was assessed using a visual analog scale at 4-6 h and at 24 h following the surgery. The secondary outcomes included complications and analgesia consumption. Results: We reviewed eight trials that included a total of 373 patients. We found no difference between the groups in postoperative pain reduction following laparoscopic TEP inguinal hernia repair. The intensity of pain was not significantly different between the bupivacaine treatment group and the control group. The pooled mean differences in pain scores were -0.26 (95 {\%} CI -0.72 to 0.21) at 4-6 h and -0.47 (95 {\%} CI -1.24 to 0.29) at 24 h. No bupivacaine-related complications were reported. Conclusion: Extraperitoneal bupivacaine treatment during laparoscopic TEP inguinal hernioplasty is not more efficacious for the reduction of postoperative pain than placebo.",
keywords = "Bupivacaine, Extraperitoneal, Inguinal hernia, Laparoscopic hernioplasty, Local anesthesia, Meta-analysis, Postoperative pain",
author = "Tong, {Y. S.} and Chien-Chih Wu and Chyi-Huey Bai and Lee, {H. C.} and Hung-Hua Liang and Li-Jen Kuo and Po-Li Wei and Ka-Wai Tam",
year = "2014",
doi = "10.1007/s10029-013-1100-0",
language = "English",
volume = "18",
pages = "177--183",
journal = "Hernia : the journal of hernias and abdominal wall surgery",
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}

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T1 - Effect of extraperitoneal bupivacaine analgesia in laparoscopic inguinal hernia repair

T2 - A meta-analysis of randomized controlled trials

AU - Tong, Y. S.

AU - Wu, Chien-Chih

AU - Bai, Chyi-Huey

AU - Lee, H. C.

AU - Liang, Hung-Hua

AU - Kuo, Li-Jen

AU - Wei, Po-Li

AU - Tam, Ka-Wai

PY - 2014

Y1 - 2014

N2 - Background: Laparoscopic total extraperitoneal (TEP) inguinal hernioplasty is significantly less painful than open repair, but it is not completely painless. Local anesthetics are thought to decrease postoperative pain when placed at the surgical site. We conducted a systematic review of randomized controlled trials (RCTs) to evaluate the efficacy of extraperitoneal bupivacaine treatment during laparoscopic inguinal hernia repair for the reduction of postoperative pain. Methods: We conducted a systematic review and meta-analysis of RCTs that investigated the outcomes of extraperitoneal bupivacaine analgesia versus control in laparoscopic TEP hernia repair. Pain was assessed using a visual analog scale at 4-6 h and at 24 h following the surgery. The secondary outcomes included complications and analgesia consumption. Results: We reviewed eight trials that included a total of 373 patients. We found no difference between the groups in postoperative pain reduction following laparoscopic TEP inguinal hernia repair. The intensity of pain was not significantly different between the bupivacaine treatment group and the control group. The pooled mean differences in pain scores were -0.26 (95 % CI -0.72 to 0.21) at 4-6 h and -0.47 (95 % CI -1.24 to 0.29) at 24 h. No bupivacaine-related complications were reported. Conclusion: Extraperitoneal bupivacaine treatment during laparoscopic TEP inguinal hernioplasty is not more efficacious for the reduction of postoperative pain than placebo.

AB - Background: Laparoscopic total extraperitoneal (TEP) inguinal hernioplasty is significantly less painful than open repair, but it is not completely painless. Local anesthetics are thought to decrease postoperative pain when placed at the surgical site. We conducted a systematic review of randomized controlled trials (RCTs) to evaluate the efficacy of extraperitoneal bupivacaine treatment during laparoscopic inguinal hernia repair for the reduction of postoperative pain. Methods: We conducted a systematic review and meta-analysis of RCTs that investigated the outcomes of extraperitoneal bupivacaine analgesia versus control in laparoscopic TEP hernia repair. Pain was assessed using a visual analog scale at 4-6 h and at 24 h following the surgery. The secondary outcomes included complications and analgesia consumption. Results: We reviewed eight trials that included a total of 373 patients. We found no difference between the groups in postoperative pain reduction following laparoscopic TEP inguinal hernia repair. The intensity of pain was not significantly different between the bupivacaine treatment group and the control group. The pooled mean differences in pain scores were -0.26 (95 % CI -0.72 to 0.21) at 4-6 h and -0.47 (95 % CI -1.24 to 0.29) at 24 h. No bupivacaine-related complications were reported. Conclusion: Extraperitoneal bupivacaine treatment during laparoscopic TEP inguinal hernioplasty is not more efficacious for the reduction of postoperative pain than placebo.

KW - Bupivacaine

KW - Extraperitoneal

KW - Inguinal hernia

KW - Laparoscopic hernioplasty

KW - Local anesthesia

KW - Meta-analysis

KW - Postoperative pain

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U2 - 10.1007/s10029-013-1100-0

DO - 10.1007/s10029-013-1100-0

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JO - Hernia : the journal of hernias and abdominal wall surgery

JF - Hernia : the journal of hernias and abdominal wall surgery

SN - 1265-4906

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