Effect of electrical discharging on formation of nanoporous biocompatible layer on Ti-6Al-4V alloys

Tzu Sen Yang, Mao Suan Huang, Mao Sheng Wang, Ming Hong Lin, Meng Yuan Tsai, Pei Yi Wang Wang

研究成果: 雜誌貢獻文章同行評審

30 引文 斯高帕斯(Scopus)

摘要

PURPOSE:: In this study, the electrical discharge machining (EDM) was formed on the surface of the Ti-6Al-4V (Ti64) specimen. MATERIALS:: The properties of adhesion and proliferation of MG-63 cells were evaluated the interactions between the EDM-treated layer and cells. RESULTS:: The incorporation of oxygen roughened the EDM-treated specimen surface on a microscale, where the nanoscale pores were superimposed. The EDM-treated layer, which can generate the thick anatase TiO2 on the Ti64 surface, afforded a cytocompatible environment. In cell culture, alkaline phosphatase activity and osteocalcin can be dramatically enhanced on the EDM-treated surfaces when compared with the untreated surface. In addition, the increase in peak currents to the EDM functionalization led to enhancement of multiple osteoblast functions. CONCLUSIONS:: This study reveals that the chemistry and crystallinity of the EDM-treated layer played important roles in affecting osteoblastic responses to the specimens, which provided insight into the development of new biomedical implant surfaces.
原文英語
頁(從 - 到)374-379
頁數6
期刊Implant Dentistry
22
發行號4
DOIs
出版狀態已發佈 - 八月 2013

ASJC Scopus subject areas

  • 口腔外科

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