Early onset Haemophilus sepsis in newborn infants: Clinical, roentgenographic, and pathologic features

L. D. Lilien, T. F. Yeh, G. M. Novak, N. M. Jacobs

研究成果: 雜誌貢獻文章

30 引文 斯高帕斯(Scopus)

摘要

Nine infants with early onset Haemophilus sepsis were seen between January 1973 and July 1977. Of the five isolated strains that were typed, only one was type B. All infants had respiratory distress, metabolic acidosis, and large alveolar arterial oxygen tension difference gradients. Eight infants weighed less than 1,500 gm and died; one infant weighed 1,701 gm and survived. Roentgenograms in six of eight showed hyaline membrane disease. Pulmonary pathologic specimens in eight infants revealed hyaline membranes in six and polymorphonuclear leukocytes in the alveolar spaces in four. In two infants, small Gram negative bacilli were noted within proteinaceous exudates in alveolar ducts. The route and time of infection in these infants with early onset Haemophilus sepsis are unclear. However, the possibility that the infection occurs before birth and that these infants represent septically aborted prematures is suggested by the high incidence of prematurity in infants with early onset Haemophilus sepsis and early detection of bacteremia in three infants.

原文英語
頁(從 - 到)299-303
頁數5
期刊Pediatrics
62
發行號3
出版狀態已發佈 - 十二月 1 1978
對外發佈Yes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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