Early Hemoperfusion May Improve Survival of Severely Paraquat-Poisoned Patients

Ching Wei Hsu, Ja Liang Lin, Dan Tzu Lin-Tan, Kuan Hsing Chen, Tzung Hai Yen, Mai Szu Wu, Shih Chieh Lin

研究成果: 雜誌貢獻文章同行評審

61 引文 斯高帕斯(Scopus)

摘要

Background: Thousands of paraquat (PQ)-poisoned patients continue to die, particularly in developing countries. Although animal studies indicate that hemoperfusion (HP) within 2-4 h after intoxication effectively reduces mortality, the effect of early HP in humans remains unknown. Methods: We analyzed the records of all PQ-poisoned patients admitted to 2 hospitals between 2000 and 2009. Patients were grouped according to early or late HP and high-dose (oral cyclophosphamide [CP] and intravenous dexamethasone [DX]) or repeated pulse (intravenous methylprednisolone [MP] and CP, followed by DX and repeated MP and/or CP) PQ therapy. Early HP was defined as HP

原文英語
文章編號e48397
期刊PLoS One
7
發行號10
DOIs
出版狀態已發佈 - 十月 29 2012
對外發佈

ASJC Scopus subject areas

  • 農業與生物科學 (全部)
  • 生物化學、遺傳與分子生物學 (全部)
  • 醫藥 (全部)

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