Dynamic MRI for tumor enhancement: An experimental breast cancer model

Ting-Kai Leung, Pai Jung Huang, Chi-Ming Lee, Chih Hsiung Wu, Yi Fan Chen, Li Kuo Shen, Wen Tien Hsiao

研究成果: 雜誌貢獻文章同行評審

2 引文 斯高帕斯(Scopus)

摘要

Dynamic contrast-enhanced magnetic resonance imaging (MRI) with post-processing is routinely used for the analysis of tumors. However, although breast MRI has gained broad clinical recognition, the relationship between imaging findings and tumor pathogenesis has yet to be fully elucidated. We grafted tumors on rats, to examine dynamic MRI images of the tumors, using post-processing subtraction with 3D maximum intensity projection (sMIP). We established a preliminary platform for analysis to compare hemodynamic-based images with histopathological findings and to further biomolecular research. This platform could facilitate future research on the mechanisms of breast tumor enhancement using MRI, improvements to MRI analysis and reduction of the false positive rate, and the development of novel drugs and contrast media.
原文英語
文章編號1350011
期刊Biomedical Engineering - Applications, Basis and Communications
25
發行號1
DOIs
出版狀態已發佈 - 二月 2013

ASJC Scopus subject areas

  • 生物物理學
  • 生物醫學工程
  • 生物工程

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