Double-Stranded RNA Sensing Determines Epithelial Cell Identity

Chung Ping Liao, Edem Tchegnon, Lu Q. Le

研究成果: 雜誌貢獻評論/辯論同行評審

摘要

Skin epithelium is constituted by heterogeneous keratinocytes in different body areas. In this issue, Zhou et al. used transcriptome analysis to investigate the site-specific epidermal cell identity on volar skin. Keratin 9 is highly enriched in volar keratinocytes, and its expression is dependent on low expression of the double-stranded RNA receptor DDX58, suggesting that double-stranded RNA sensing could allow a potential approach to modulate skin thickness and durability.
原文英語
頁(從 - 到)17-19
頁數3
期刊Journal of Investigative Dermatology
139
發行號1
DOIs
出版狀態已發佈 - 一月 2019

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

指紋 深入研究「Double-Stranded RNA Sensing Determines Epithelial Cell Identity」主題。共同形成了獨特的指紋。

引用此