Dose-response relationships of oral habits associated with the risk of oral pre-malignant lesions among men who chew betel quid

Amy Ming Fang Yen, Shao Ching Chen, Tony Hsiu Hsi Chen

研究成果: 雜誌貢獻文章

46 引文 (Scopus)

摘要

Betel quid, cigarettes and alcohol are well-recognized risk factors for oral cancer. However, the combined effect of the frequency and duration of these oral habits on the risk for developing oral pre-malignancies among betel quid users has not been fully addressed. In this study, an oral screening programme for men chewing betel quid was carried out by well-trained dentists for early detection of oral pre-malignancy lesions. Using generalized logit model and proportional odds model, we found that, compared with the occasional user, the adjusted odds ratios of developing leukoplakia for men chewing one to 10 pieces of betel quid, 11-20 pieces, and more than 20 pieces per day were estimated as 2.14 (95% confidence interval [CI] 1.62-2.81), 2.99 (95% CI 2.06-4.27), and 5.37 (95% CI 3.76-7.47), respectively. The corresponding figures for erythroleukoplakia were 3.69 (95% CI 1.55-8.79), 13.78 (95% CI 5.76-32.98), and 36.64 (95% CI 15.94-84.16), respectively. Similar results were found while the duration was considered. The dose-response relationships were not as noteworthy for cigarette and alcohol drinking.
原文英語
頁(從 - 到)634-638
頁數5
期刊Oral Oncology
43
發行號7
DOIs
出版狀態已發佈 - 八月 2007
對外發佈Yes

指紋

Habits
Confidence Intervals
Mastication
Tobacco Products
Leukoplakia
Mouth Neoplasms
Dentists
Alcohol Drinking
Neoplasms
Logistic Models
Odds Ratio
Alcohols

ASJC Scopus subject areas

  • Oncology

引用此文

Dose-response relationships of oral habits associated with the risk of oral pre-malignant lesions among men who chew betel quid. / Yen, Amy Ming Fang; Chen, Shao Ching; Chen, Tony Hsiu Hsi.

於: Oral Oncology, 卷 43, 編號 7, 08.2007, p. 634-638.

研究成果: 雜誌貢獻文章

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abstract = "Betel quid, cigarettes and alcohol are well-recognized risk factors for oral cancer. However, the combined effect of the frequency and duration of these oral habits on the risk for developing oral pre-malignancies among betel quid users has not been fully addressed. In this study, an oral screening programme for men chewing betel quid was carried out by well-trained dentists for early detection of oral pre-malignancy lesions. Using generalized logit model and proportional odds model, we found that, compared with the occasional user, the adjusted odds ratios of developing leukoplakia for men chewing one to 10 pieces of betel quid, 11-20 pieces, and more than 20 pieces per day were estimated as 2.14 (95{\%} confidence interval [CI] 1.62-2.81), 2.99 (95{\%} CI 2.06-4.27), and 5.37 (95{\%} CI 3.76-7.47), respectively. The corresponding figures for erythroleukoplakia were 3.69 (95{\%} CI 1.55-8.79), 13.78 (95{\%} CI 5.76-32.98), and 36.64 (95{\%} CI 15.94-84.16), respectively. Similar results were found while the duration was considered. The dose-response relationships were not as noteworthy for cigarette and alcohol drinking.",
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