摘要
原文 | 英語 |
---|---|
頁(從 - 到) | 1843-1851 |
頁數 | 9 |
期刊 | Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering |
卷 | 42 |
發行號 | 12 |
DOIs | |
出版狀態 | 已發佈 - 十月 2007 |
指紋
ASJC Scopus subject areas
- Environmental Engineering
- Environmental Science(all)
- Environmental Chemistry
引用此文
Dose-response relationship between ingested arsenic and cataracts among residents in Southwestern Taiwan. / See, Lai Chu; Chiou, Hung-Yi; Lee, Jiahn Shing; Hsueh, Yu-Mei; Lin, Shu Mei; Tu, Ming Chang; Yang, Meng Ling; Chen, Chien Jen.
於: Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering, 卷 42, 編號 12, 10.2007, p. 1843-1851.研究成果: 雜誌貢獻 › 文章
}
TY - JOUR
T1 - Dose-response relationship between ingested arsenic and cataracts among residents in Southwestern Taiwan
AU - See, Lai Chu
AU - Chiou, Hung-Yi
AU - Lee, Jiahn Shing
AU - Hsueh, Yu-Mei
AU - Lin, Shu Mei
AU - Tu, Ming Chang
AU - Yang, Meng Ling
AU - Chen, Chien Jen
PY - 2007/10
Y1 - 2007/10
N2 - This association study was carried out to examine the effect of long-term exposure to ingested arsenic on various types of cataract. A total of 349 residents living in arseniasis-hyperendemic villages of southwestern Taiwan were recruited. Cumulative arsenic exposure was derived from the history of consuming artesian well water and the arsenic level in well water. The Lens Opacities System III was used to classify different types of cataract. The cataract surgery prevalence was 10% for the age group of 50 or more years. Cortical opacity was most common (35%), while nuclear and posterior subcapsular opacities were observed in 24% and 22% of subjects, respectively. Diabetes mellitus was a significant risk factor for all types of cataract. Occupational sunlight exposure was associated with cortical and posterior subcapsular opacities in a dose-response relationship. The cumulative exposure to arsenic from artesian well water and the duration of consuming artesian well water were associated with an increased risk of all types of lens opacity. But statistically significant dose-response relations with the cumulative arsenic exposure and the duration of consuming artesian well water were observed only for posterior subcapsular opacity (P = 0.014 and P = 0.023, respectively) after adjustment for age, sex, diabetes status, and occupational sunlight exposure. It was concluded that there was an increasing prevalence of posterior subcapsular opacity with the increase in exposure to ingested arsenic.
AB - This association study was carried out to examine the effect of long-term exposure to ingested arsenic on various types of cataract. A total of 349 residents living in arseniasis-hyperendemic villages of southwestern Taiwan were recruited. Cumulative arsenic exposure was derived from the history of consuming artesian well water and the arsenic level in well water. The Lens Opacities System III was used to classify different types of cataract. The cataract surgery prevalence was 10% for the age group of 50 or more years. Cortical opacity was most common (35%), while nuclear and posterior subcapsular opacities were observed in 24% and 22% of subjects, respectively. Diabetes mellitus was a significant risk factor for all types of cataract. Occupational sunlight exposure was associated with cortical and posterior subcapsular opacities in a dose-response relationship. The cumulative exposure to arsenic from artesian well water and the duration of consuming artesian well water were associated with an increased risk of all types of lens opacity. But statistically significant dose-response relations with the cumulative arsenic exposure and the duration of consuming artesian well water were observed only for posterior subcapsular opacity (P = 0.014 and P = 0.023, respectively) after adjustment for age, sex, diabetes status, and occupational sunlight exposure. It was concluded that there was an increasing prevalence of posterior subcapsular opacity with the increase in exposure to ingested arsenic.
KW - Cataract
KW - Ingested arsenic
KW - Posterior subcapsular opacities
KW - Prevalence
UR - http://www.scopus.com/inward/record.url?scp=35348948117&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=35348948117&partnerID=8YFLogxK
U2 - 10.1080/10934520701566884
DO - 10.1080/10934520701566884
M3 - Article
C2 - 17952785
AN - SCOPUS:35348948117
VL - 42
SP - 1843
EP - 1851
JO - Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering
JF - Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering
SN - 1093-4529
IS - 12
ER -