Direct and selective metal-free N6-arylation of adenosine residues for simple fluorescence labeling of DNA and RNA

Guralamatta Siddappa Ravi Kumara, Anup Pandith, Young Jun Seo

研究成果: 雜誌貢獻文章同行評審

4 引文 斯高帕斯(Scopus)

摘要

We have developed an unprecedented transition metal-free approach for the direct fluorescence turn-on labeling of natural oligonucleotides through selective N6-arylation of adenosine moieties. This method allows the simple and direct fluorescence labeling of natural unmodified DNA and RNA, but is dependent on the secondary structure, favoring single-stranded structures.
原文英語
頁(從 - 到)5450-5453
頁數4
期刊Chemical Communications
57
發行號44
DOIs
出版狀態已發佈 - 6月 4 2021
對外發佈

ASJC Scopus subject areas

  • 催化
  • 電子、光磁材料
  • 陶瓷和複合材料
  • 化學 (全部)
  • 表面、塗料和薄膜
  • 金屬和合金
  • 材料化學

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