Digital interventions self-management education for type 1 and 2 diabetes: A systematic review and meta-analysis

Dumisani Enricho Nkhoma, Charles Jenya Soko, Pierre Bowrin, Yankuba B. Manga, David Greenfield, Mowafa Househ, Yu-Chuan Li, Usman Iqbal

研究成果: 雜誌貢獻文章同行評審

6 引文 斯高帕斯(Scopus)


Objective: To describe and assess digital health-led diabetes self-management education and support (DSMES) effectiveness in improving glycosylated hemoglobin, diabetes knowledge, and health-related quality of life (HrQoL) of Type 1 and 2 Diabetes in the past 10 years. Design: Systematic Review and Meta-Analysis. The protocol was registered on PROSPERO registration number CRD42019139884. Data Sources: PubMed, EMBASE, Cochrane library, Web of Science, and Scopus between January 2010 and August 2019. Study Selection and Appraisal: Randomized control trials of digital health-led DSMES for Type 1 (T1DM) or 2 (T2DM) diabetes compared to usual care were included. Outcomes were change in HbA1c, diabetes knowledge, and HrQoL. Cochrane Risk of Bias 2.0 tool was used to assess bias and GRADEpro for overall quality. The analysis involved narrative synthesis, subgroup and pooled meta-analyses. Results: From 4286 articles, 39 studies (6861 participants) were included. Mean age was 51.62 years, range (13–70). Meta-analysis revealed intervention effects on HbA1c for T2DM with difference in means (MD) from baseline -0.480% (-0.661, -0.299), I275% (6 months), -0.457% (-0.761, -0.151), I2 81% (12 months), and for T1DM -0.41% (-1.022, 0.208) I2 83% (6 months), -0.03% (-0.210, 0.142) I2 0% (12 months). Few reported HrQoL with Hedges’ g 0.183 (-0.039, 0.405), I2 0% (6 months), 0.153 (-0.060, 0.366), I2 0% (12 months) and diabetes knowledge with Hedges’ g 1.003 (0.068, 1.938), I2 87% (3 months). Conclusion: Digital health-led DSMES are effective in improving HbA1c and diabetes knowledge, notably for T2DM. Research shows non-significant changes in HrQoL. Intervention effect on HbA1c was more impressive if delivered through mobile apps or patient portals. Further research is needed on the impact of DSMES on these outcomes, especially for newly diagnosed diabetes patients.

期刊Computer Methods and Programs in Biomedicine
出版狀態已發佈 - 10月 2021

ASJC Scopus subject areas

  • 軟體
  • 電腦科學應用
  • 健康資訊學


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