Diagnostic value of EBUS-TBNA for lung cancer with non-enlarged lymph nodes: A study in a Tuberculosis-Endemic Country

Chih Hsi Kuo, Hao Cheng Chen, Fu Tsai Chung, Yu Lun Lo, Kang Yun Lee, Chih Wei Wang, Wen Han Kuo, Tzu Chen Yen, Han Pin Kuo

研究成果: 雜誌貢獻文章同行評審

29 引文 斯高帕斯(Scopus)

摘要

Background: In tuberculosis (TB)-endemic areas, contrast-enhanced computed tomography (CT) and positron emission tomography (PET) findings of lung cancer patients with non-enlarged lymph nodes are frequently discrepant. Endobronchial ultrasound-guided transbronchial aspiration (EBUS-TBNA) enables real-time nodal sampling, and thereby improves nodal diagnosis accuracy. This study aimed to compare the accuracy of nodal diagnosis by using EBUS-TBNA, and PET. Methods: We studied 43 lung cancer patients with CT-defined non-enlarged mediastinal and hilar lymph nodes and examined 78 lymph nodes using EBUS-TBNA. Results: The sensitivity, specificity, positive predictive value, and negative predictive value of EBUS-TBNA were 80.6%, 100%, 100%, and 85.7%, respectively. PET had low specificity (18.9%) and a low positive predictive value (44.4%). The diagnostic accuracy of EBUS-TBNA was higher than that of PET (91% vs. 47.4%; p
原文英語
文章編號e16877
期刊PLoS ONE
6
發行號2
DOIs
出版狀態已發佈 - 2011
對外發佈

ASJC Scopus subject areas

  • 多學科

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