摘要

In this study, the chitosan-polyglutamate hydrogel was developed as injectable polyelectrolyte complex (PEC) scaffold for bone regeneration. In practice, oppositely charged polyelectrolytes were mixed using a static injection mixer, the gelation time was less than 1 min. The resorbable PEC scaffold can be in situ-formed as a scaffold for osteoblast ingrowth. The canine alveolar defect model was used to evaluate the efficacy of PEC implants. The PEC scaffold was highly effective in enhancing bone regeneration. Moreover, the addition of CaSO4·2H2O (CSD) to PEC scaffold can further enhance the early stage healing of bone regeneration.
原文英語
頁(從 - 到)318-324
頁數7
期刊Carbohydrate Polymers
85
發行號2
DOIs
出版狀態已發佈 - 五月 6 2011

    指紋

ASJC Scopus subject areas

  • Organic Chemistry
  • Materials Chemistry
  • Polymers and Plastics

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