Development of a biochip using antibody-coated gold nanoparticles to detect specific bioparticles

Jung Tang Huang, Shao Y. Hou, Shiuh B. Fang, Hua W. Yu, Hung Chan Lee, Chu Z. Yang

研究成果: 雜誌貢獻文章同行評審

13 引文 斯高帕斯(Scopus)

摘要

This study developed a method of detecting bioparticles such as Salmonella that exist in the biological samples. The method employed a substrate with interlaced comb-like electrodes into which the mixtures of biological samples and antibody-coated gold nanoparticles were added. The alternative signals with appropriate frequency bands were then conducted into the comb-like electrodes to change the dielectrophoresis force. The gold-modified Salmonella can be adsorbed on the edges of the electrodes and isolated from various biological samples. The impedance of the adsorbed Salmonella on the edges of the electrodes was measured and comparison of the impedance between the electrodes with and without Salmonella can quantify the amount of the adsorbed Salmonella.

原文英語
頁(從 - 到)1377-1385
頁數9
期刊Journal of Industrial Microbiology and Biotechnology
35
發行號11
DOIs
出版狀態已發佈 - 十一月 2008
對外發佈

ASJC Scopus subject areas

  • 生物技術
  • 應用微生物與生物技術

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