Determinants of the creatinine clearance to glomerular filtration rate ratio in patients with chronic kidney disease: A cross-sectional study

Yen Chung Lin, Nisha Bansal, Eric Vittinghoff, Alan S. Go, Chi Yuan Hsu

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8 引文 斯高帕斯(Scopus)

摘要

Background: Creatinine secretion, as quantified by the ratio of creatinine clearance (CrCl) to glomerular filtration rate (GFR), may introduce another source of error when using serum creatinine concentration to estimate GFR. Few studies have examined determinants of the CrCl/GFR ratio. We sought to study whether higher levels of albuminuria would be associated with higher, and being non-Hispanic black with lower, CrCl/GFR ratio. Methods. We did a cross-sectional analysis of 1342 patients with chronic kidney disease from the Chronic Renal Insufficiency Cohort (CRIC) who had baseline measure of iothalamate GFR (iGFR) and 24-hour urine collections. Our predictors included urine albumin as determined from 24-hour urine collections (categorized as:

原文英語
文章編號268
期刊BMC Nephrology
14
發行號1
DOIs
出版狀態已發佈 - 十二月 5 2013

ASJC Scopus subject areas

  • Nephrology

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