Detection of C-reactive protein based on measurement of Brownian motion by micro-particle-tracking-velocimetry

Y. J. Fan, Chiajui Hsu, Chengpang Liu, Tzuheng Wu, Horn Jiunn Sheen, Shyhfeng Lin

研究成果: 書貢獻/報告類型會議貢獻

2 引文 斯高帕斯(Scopus)

摘要

A novel bio-sensing technique based on Brownian motion change with use of a micro-particle-tracking-velocimetry (micro-PTV) has been successfully developed to measure the antigen-antibody interactions. The rapid interaction between antigen, C-reactive protein (CRP), and the nanobeads conjugated with antibody, anti-CRP, enabled the real-time detection of CRP to be easily carried out. During the binding process of nanobeads to CRP, the mean value of the beads diameter increased so that the Brownian velocity decreased with increasing time. Moreover, higher CRP concentration led to lower Brownian velocity of the nanobead at equilibrium state. Furthermore, the sensitivity was raised when the smaller nanobeads were used.
原文英語
主出版物標題MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems
頁面192-195
頁數4
DOIs
出版狀態已發佈 - 2008
對外發佈
事件21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson - Tucson, AZ, 美国
持續時間: 一月 13 2008一月 17 2008

會議

會議21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson
國家/地區美国
城市Tucson, AZ
期間1/13/081/17/08

ASJC Scopus subject areas

  • 機械工業
  • 電氣與電子工程
  • 控制與系統工程

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