Dermal delivery by niosomes of black tea extract as a sunscreen agent

Meng I. Yeh, Hsiu Chin Huang, Jia Horng Liaw, Min Chuan Huang, Kuei Fen Huang, Feng-Lin Hsu

研究成果: 雜誌貢獻文章同行評審

12 引文 斯高帕斯(Scopus)

摘要

Objectives The primary objective of this study was to investigate the feasibility of using niosomes as a delivery vehicle for the dermal administration in vitro of black tea extract (BTE) as a sunscreen. Methods Multi-lamellar niosomes were obtained by means of a previously reported method of lipid hydration films. In vitro penetration experiments through nude mouse skin were carried out to evaluate the potential of niosomes as a dermal formulation. The nude mouse skin membrane allowed the effects of penetration with a niosome formulation to be evaluated. Penetration rates of caffeine- and gallic acid-loaded niosomes in a steady state were higher than dispersion in aqueous solutions. Results For skin permeation, higher transdermal absorption rates were seen with solutions of caffeine and gallic acid. Conclusions In the near future, BTE as a sunscreen agent will be dermally delivered by niosomes.

原文英語
頁(從 - 到)239-245
頁數7
期刊International Journal of Dermatology
52
發行號2
DOIs
出版狀態已發佈 - 二月 2013

ASJC Scopus subject areas

  • 皮膚科

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