Depression and cholesteatoma: Preliminary findings from a nationwide population-based retrospective cohort study

Chin Lung Kuo, Nancy Hsaoyen Chang, An Suey Shiao, Chiang Feng Lien, Hsiao Ling Huang, Szu Hai Lin, Wei Pin Chang

研究成果: 雜誌貢獻文章同行評審

3 引文 斯高帕斯(Scopus)

摘要

Objective To estimate the risk of developing depressive disorder (DD) following diagnosis with cholesteatoma. Methods In the study, we analyzed data from the Longitudinal Health Insurance Database of Taiwan. A total of 599 patients newly diagnosed with cholesteatoma between 1997 and 2007 were included with a comparison cohort of 2995 matched non-cholesteatoma enrollees. Each patient was followed for 3 years to identify the subsequent development of DD. Cox proportional hazard regression analysis was performed to compute adjusted 3-year hazard ratios. Results The incidence of DD per thousand person-years was approximately twice as high among patients with cholesteatoma (11.32) as among those without cholesteatoma (5.85). After adjusting for potential confounders, patients with cholesteatoma were 1.99 times (95% CI=1.18-3.34, P=0.010) more likely to suffer from DD within 3 years compared to those without cholesteatoma. Conclusions This is the first study to demonstrate a link between cholesteatoma and subsequent DD within a three-year followup. We suggest that clinicians keep this critical but neglected issue in mind and carefully investigate the possibility of subsequent psychological problems among cholesteatoma patients.
原文英語
頁(從 - 到)222-225
頁數4
期刊Journal of Affective Disorders
194
DOIs
出版狀態已發佈 - 四月 1 2016

Keywords

  • Cholesteatoma
  • Depression
  • Population-based study

ASJC Scopus subject areas

  • 精神病學和心理健康
  • 臨床心理學

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