Delivery and targeting of nanoparticles into hair follicles

Chia Lang Fang, Ibrahim A. Aljuffali, Yi Ching Li, Jia You Fang

研究成果: 雜誌貢獻文章同行評審

73 引文 斯高帕斯(Scopus)

摘要

It has been demonstrated that nanoparticles used for follicular delivery provide some advantages over conventional pathways, including improved skin bioavailability, enhanced penetration depth, prolonged residence duration, fast transport into the skin and tissue targeting. This review describes recent developments using nanotechnology approaches for drug delivery into the follicles. Different types of nanosystems may be employed for management of follicular permeation, such as polymeric nanoparticles, metallic nanocrystals, liposomes, and lipid nanoparticles. This review systematically introduces the mechanisms of follicles for nanoparticulate penetration, highlighting the therapeutic potential of drug-loaded nanoparticles for treating skin diseases. Special attention is paid to the use of nanoparticles in treating appendage-related disorders, in particular, nanomedical strategies for treating alopecia, acne, and transcutaneous immunization.

原文英語
頁(從 - 到)991-1006
頁數16
期刊Therapeutic Delivery
5
發行號9
DOIs
出版狀態已發佈 - 9月 1 2014

ASJC Scopus subject areas

  • 藥學科學

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