Degradation of antibiotic amoxicillin using 1×1 molecular sieve-structured manganese oxide

Wen Hui Kuan, Ching Yao Hu, Bin Sheng Liu, Yu Min Tzou

研究成果: 雜誌貢獻文章

4 引文 (Scopus)

摘要

The kinetics and mechanism of amoxicillin (AMO) degradation using a 1×1 molecular sieve-structured manganese oxide (MnO2) was studied. The presence of the buffer solution (i.e., NaHCO3, NaH 2PO4 and KH2PO4) diminished AMO binding to MnO2, thus reducing AMO degradation in the pretest; therefore, all other experiments in this study were conducted without the addition of a buffer. Third-order rate constants, second-order on AMO and first-order on MnO2 increased with elevating pH level (2.81-7.23) from 0.54 to 9.17 M-2 s-1, and it decreased to 4.27 M -2 s-1 at pH 8.53 beyond the pka2 of AMO (7.3). The dissolution of the MnO2 suspension with and without AMO exhibited a similar trend; that is, Mn2+ concentration increased with decreasing pH. However, the dissolution of MnO2 with AMO was greater than that without AMO, except for the reaction occurring at pH 8.53, partially indicating that MnO2 acts as an oxidant in AMO degradation. The preliminary chromatogram data display different products with varying pH reaction s, implying that AMO elimination using this 1×1 molecular sieve-structured MnO2 is by adsorption as well as oxidative degradation. A complementary experiment indicates that the amount of oxidatively degraded AMO increases substantially from 65.5% at 4 h to 95% at 48 h, whereas the AMO adsorbed onto MnO2 decreases slightly from 4.5% at 4 h to 2.4% at 48 h. The oxidative degradation accounted for more AMO removal than adsorption over the whole reaction course, indicating that the oxidative reaction of AMO on MnO2 dominated the AMO removal.

原文英語
頁(從 - 到)2443-2451
頁數9
期刊Environmental Technology
34
發行號16
DOIs
出版狀態已發佈 - 八月 1 2013

指紋

manganese oxide
Amoxicillin
Molecular sieves
antibiotics
Anti-Bacterial Agents
Degradation
degradation
dissolution
adsorption
oxidant
experiment
kinetics
Buffers
Dissolution
Adsorption
Oxidants
removal

ASJC Scopus subject areas

  • Environmental Chemistry
  • Waste Management and Disposal
  • Water Science and Technology

引用此文

Degradation of antibiotic amoxicillin using 1×1 molecular sieve-structured manganese oxide. / Kuan, Wen Hui; Hu, Ching Yao; Liu, Bin Sheng; Tzou, Yu Min.

於: Environmental Technology, 卷 34, 編號 16, 01.08.2013, p. 2443-2451.

研究成果: 雜誌貢獻文章

Kuan, Wen Hui ; Hu, Ching Yao ; Liu, Bin Sheng ; Tzou, Yu Min. / Degradation of antibiotic amoxicillin using 1×1 molecular sieve-structured manganese oxide. 於: Environmental Technology. 2013 ; 卷 34, 編號 16. 頁 2443-2451.
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abstract = "The kinetics and mechanism of amoxicillin (AMO) degradation using a 1×1 molecular sieve-structured manganese oxide (MnO2) was studied. The presence of the buffer solution (i.e., NaHCO3, NaH 2PO4 and KH2PO4) diminished AMO binding to MnO2, thus reducing AMO degradation in the pretest; therefore, all other experiments in this study were conducted without the addition of a buffer. Third-order rate constants, second-order on AMO and first-order on MnO2 increased with elevating pH level (2.81-7.23) from 0.54 to 9.17 M-2 s-1, and it decreased to 4.27 M -2 s-1 at pH 8.53 beyond the pka2 of AMO (7.3). The dissolution of the MnO2 suspension with and without AMO exhibited a similar trend; that is, Mn2+ concentration increased with decreasing pH. However, the dissolution of MnO2 with AMO was greater than that without AMO, except for the reaction occurring at pH 8.53, partially indicating that MnO2 acts as an oxidant in AMO degradation. The preliminary chromatogram data display different products with varying pH reaction s, implying that AMO elimination using this 1×1 molecular sieve-structured MnO2 is by adsorption as well as oxidative degradation. A complementary experiment indicates that the amount of oxidatively degraded AMO increases substantially from 65.5{\%} at 4 h to 95{\%} at 48 h, whereas the AMO adsorbed onto MnO2 decreases slightly from 4.5{\%} at 4 h to 2.4{\%} at 48 h. The oxidative degradation accounted for more AMO removal than adsorption over the whole reaction course, indicating that the oxidative reaction of AMO on MnO2 dominated the AMO removal.",
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N2 - The kinetics and mechanism of amoxicillin (AMO) degradation using a 1×1 molecular sieve-structured manganese oxide (MnO2) was studied. The presence of the buffer solution (i.e., NaHCO3, NaH 2PO4 and KH2PO4) diminished AMO binding to MnO2, thus reducing AMO degradation in the pretest; therefore, all other experiments in this study were conducted without the addition of a buffer. Third-order rate constants, second-order on AMO and first-order on MnO2 increased with elevating pH level (2.81-7.23) from 0.54 to 9.17 M-2 s-1, and it decreased to 4.27 M -2 s-1 at pH 8.53 beyond the pka2 of AMO (7.3). The dissolution of the MnO2 suspension with and without AMO exhibited a similar trend; that is, Mn2+ concentration increased with decreasing pH. However, the dissolution of MnO2 with AMO was greater than that without AMO, except for the reaction occurring at pH 8.53, partially indicating that MnO2 acts as an oxidant in AMO degradation. The preliminary chromatogram data display different products with varying pH reaction s, implying that AMO elimination using this 1×1 molecular sieve-structured MnO2 is by adsorption as well as oxidative degradation. A complementary experiment indicates that the amount of oxidatively degraded AMO increases substantially from 65.5% at 4 h to 95% at 48 h, whereas the AMO adsorbed onto MnO2 decreases slightly from 4.5% at 4 h to 2.4% at 48 h. The oxidative degradation accounted for more AMO removal than adsorption over the whole reaction course, indicating that the oxidative reaction of AMO on MnO2 dominated the AMO removal.

AB - The kinetics and mechanism of amoxicillin (AMO) degradation using a 1×1 molecular sieve-structured manganese oxide (MnO2) was studied. The presence of the buffer solution (i.e., NaHCO3, NaH 2PO4 and KH2PO4) diminished AMO binding to MnO2, thus reducing AMO degradation in the pretest; therefore, all other experiments in this study were conducted without the addition of a buffer. Third-order rate constants, second-order on AMO and first-order on MnO2 increased with elevating pH level (2.81-7.23) from 0.54 to 9.17 M-2 s-1, and it decreased to 4.27 M -2 s-1 at pH 8.53 beyond the pka2 of AMO (7.3). The dissolution of the MnO2 suspension with and without AMO exhibited a similar trend; that is, Mn2+ concentration increased with decreasing pH. However, the dissolution of MnO2 with AMO was greater than that without AMO, except for the reaction occurring at pH 8.53, partially indicating that MnO2 acts as an oxidant in AMO degradation. The preliminary chromatogram data display different products with varying pH reaction s, implying that AMO elimination using this 1×1 molecular sieve-structured MnO2 is by adsorption as well as oxidative degradation. A complementary experiment indicates that the amount of oxidatively degraded AMO increases substantially from 65.5% at 4 h to 95% at 48 h, whereas the AMO adsorbed onto MnO2 decreases slightly from 4.5% at 4 h to 2.4% at 48 h. The oxidative degradation accounted for more AMO removal than adsorption over the whole reaction course, indicating that the oxidative reaction of AMO on MnO2 dominated the AMO removal.

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