CYTOGENETICALLY ABNORMAL CELL S IN VITRO IN ACUTE LEUKÆMIA

M. J. Duttera, J. M.C. Bull, J. Whang-Peng, P. P. Carbone

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)

摘要

Twenty patients with previously identified direct cytogenetic abnormalities were examined for persistence of the abnormality in both direct bone-marrow preparations and in-vitro methylcellulose cultures. Of seven patients with persistent direct abnormalities, four had these same cytogenetic abnormalities identified in cells from culture. In three patients with acute myelocytic leukæmia or a variant, these abnormalities had been previously associated with leukæmic cell lines. Cytogenetic markers in the cultured cells indicate that leukæmic cells from some patients can be grown in vitro.
原文英語
頁(從 - 到)715-718
頁數4
期刊The Lancet
299
發行號7753
DOIs
出版狀態已發佈 - 四月 1 1972
對外發佈Yes

ASJC Scopus subject areas

  • Medicine(all)

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