Cytogenetic characterization of selected small round cell tumors of childhood

J. Whang-Peng, T. J. Triche, T. Knutsen, J. Miser, S. Kao-Shan, S. Tsai, M. A. Israel

研究成果: 雜誌貢獻文章

264 引文 斯高帕斯(Scopus)

摘要

Small, round, blue-cell tumors (SRCT), including rhabdomyosarcoma, Ewing's sarcoma of bone and soft tissue, mesenchymal chondrosarcoma, small cell osteosarcoma, hemangiopericytoma, neuroblastoma, peripheral neurectodermal tumor (peripheral neuroepithelioma of bone and soft tissue), and the malignant small cell tumor of the thoracopulmonary region described by Askin (Askin's tumor), are often difficult to distinguish by light microscopy. We have evaluated the cytogenetics of these tumors by studying 24 tumor explants in short-term culture and 22 tumor cell lines. In Ewing's sarcoma (a tumor of unknown histogenesis), and in peripheral neuroepithelioma and Askin's tumor (tumors with evidence of neural origin), we have observed an indistinguishable t(11;22) translocation.
原文英語
頁(從 - 到)185-208
頁數24
期刊Cancer Genetics and Cytogenetics
21
發行號3
DOIs
出版狀態已發佈 - 四月 1 1986
對外發佈Yes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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