@inproceedings{178ab45a0beb4974b3ee910d4ffc222c,
title = "CTCs detection by SACA chip and image analysis",
abstract = "Immunofluorescence is widely used in detection and characterization of circulating tumor cells (CTCs). The process of immunofluorescence staining on cells needs centrifugal force to wash residual fluorescence, which is not only time consuming but also cells harmful. To speed up the staining process, a three-dimensional (3D) microfluidic device is employed in this work. This study also reports the rapid selection of identified live CTCs from whole blood on SACA chip for further characterization by automatic imaging and in-situ cell capturing process. The whole process takes 120 minutes for examining 4 ml whole blood sample and the recognition sensitivity can approach 1/108 by using the integrated chip and automatic image system. All cells are remained highly viable after the rapid selection process for further applications.",
keywords = "automatic detection, circulating tumor cell, SACA chip",
author = "Wanying Cho and Weng, {Yi Hsuan} and Chen, {Hsin Ying} and Chu, {Hsueh Yao} and Chiou, {Tzeon Jye} and Lin, {Chien Ping} and Jiang, {Jeng Kai} and Yang, {Chih Yung} and Tseng, {Fan Gang}",
note = "Funding Information: ACKNOWLEDGMENT This research was financially supported by the Ministry of Science and Technology of the Republic of China. Publisher Copyright: {\textcopyright} 2017 IEEE.; 12th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017 ; Conference date: 09-04-2017 Through 12-04-2017",
year = "2017",
month = aug,
day = "25",
doi = "10.1109/NEMS.2017.8017042",
language = "English",
series = "2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "360--363",
booktitle = "2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017",
address = "United States",
}