Cryptogenic pyogenic liver abscess as a sign of colorectal cancer: A population-based 5-year follow-up study

Hsueh Chou Lai, Herng Ching Lin

研究成果: 雜誌貢獻文章

27 引文 斯高帕斯(Scopus)

摘要

Background/aims: No large-scale population-based study has ever been conducted to examine the relationship between cryptogenic pyogenic liver abscesses (PLA) and the subsequent risk of colorectal cancer. This study aimed to estimate the risk for colorectal cancer following a diagnosis of cryptogenic PLA over a 5-year period. Methods: The study group comprised 274 patients who visited an outpatient care centre or were hospitalized with a diagnosis of cryptogenic PLA between 2001 and 2003. The comparison group included 1370 randomly selected subjects. Cox proportional hazard regressions were performed to compare the 5-year colorectal cancer-free survival rates for these two groups. Results: Of the total sample, 40 patients from the study group (2.43%) had colorectal cancer during the 5-year follow-up period: 15 (5.45% of those with cryptogenic PLA) and 25 from the comparison group (1.82% of the comparison group). After adjusting for patients' age, sex, monthly income, level of urbanization and geographical location, the hazard of colorectal cancer during the 5-year period was 3.36 times greater for patients with cryptogenic PLA than for the comparison group [95% confidence interval (CI)=1.72-6.56, P

原文英語
頁(從 - 到)1387-1393
頁數7
期刊Liver International
30
發行號9
DOIs
出版狀態已發佈 - 十月 2010

ASJC Scopus subject areas

  • Hepatology

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