Cortisol awakening response in patients with bipolar disorder during acute episodes and partial remission: A pilot study

Ming Chyi Huang, Shan Chi Chuang, Mei Chih Meg Tseng, Yi Ling Chien, Shih Cheng Liao, Hsi Chung Chen, Po Hsiu Kuo

研究成果: 雜誌貢獻文章同行評審

8 引文 斯高帕斯(Scopus)

摘要

This exploratory study examined the cortisol awakening response (CAR) in patients with bipolar disorder (BPD) at acute phases and partial remission of manic or depressive episodes. Saliva samples of twenty-seven BPD inpatients and 25 healthy controls were collected to determine the CAR patterns, and 12 patients were sampled again at partial remission. BPD patients exhibited a non-enhanced CAR pattern. Lower cortisol expression and a blunted CAR distinguished bipolar-depressive patients from the controls. The intra-individual follow-up for both patient groups revealed a non-significant improvement in CAR patterns, indicating a trend of a normalized CAR after partial remission for BPD patients.

原文英語
頁(從 - 到)594-597
頁數4
期刊Psychiatry Research
258
DOIs
出版狀態已發佈 - 12月 2017

ASJC Scopus subject areas

  • 精神病學和心理健康
  • 生物精神病學

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