Correlation between joint [F-18] FDG PET uptake and synovial TNF-α concentration: A study with two rabbit models of acute inflammatory arthritis

Po Wei Lin, Ren Shyan Liu, Tsan Hon Liou, Li Chern Pan, Chi-Hsien Chen

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)

摘要

The objective of this study was to verify that the [F-18]FDG PET synovial uptake is correlated with the synovial fluid (SF) TNF-α concentration. Two rabbit models of acute inflammatory arthritis induced by human interleukin-8 and lipopolysaccharide were used. Modified standard uptake values (MSUVs) obtained from PET images of the animals were compared with results of SF TNF-α measurements. Statistically significant correlations were found between the MSUVs and the SF TNF-α ratios. An equation to estimate the TNF-α ratio from a MSUV was also derived.
原文英語
頁(從 - 到)1221-1226
頁數6
期刊Applied Radiation and Isotopes
65
發行號11
DOIs
出版狀態已發佈 - 十一月 2007

    指紋

ASJC Scopus subject areas

  • Radiation

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