1 引文 (Scopus)

摘要

OBJECTIVE: Anxiety and depression are risk factors for obstructive coronary artery disease (CAD), but their effects on coronary artery spasm (CAS) remain unestablished. METHODS: Patient records in this population-based study were retrospectively collected from the Taiwan National Health Insurance Research Database. Using propensity score matching, we used 1:1:1 ratio stratification into a control group of 10,325 individuals without CAS or CAD, a CAS group comprising 10,473 patients, and a CAD group comprising 10,473 patients during 2000-2012. RESULTS: The prevalence of CAS and CAD was 0.067% and 8.7%, respectively, in the general population. The prevalence of anxiety and depression diagnoses was significantly higher in patients with new-onset CAS than in those with new-onset CAD and controls without CAS/CAD, even after propensity score matching. Compared with CAD, anxiety and depression diagnoses conferred a higher risk of developing CAS (odds ratio [OR] = 2.29, 95% confidence interval [CI], 2.14-2.45, p < .001, and OR = 1.34, 95% CI, 1.08-1.66, p = .007, respectively). The association was even stronger when comparing CAS with the control group without CAD or CAS (OR = 5.20, 95% CI, 4.72-5.74, p < .001, and OR = 1.98, 95% CI, 1.50-2.62, p < .001, respectively). The increased risk of new-onset CAS as related to previous anxiety and depression diagnoses was comparable between males and females. CONCLUSIONS: Compared with CAD or the general population, anxiety and depression diagnoses confer a higher risk of developing CAS. No sex differences are found for the association of anxiety and depression with CAS.
原文英語
頁(從 - 到)237-245
頁數9
期刊Psychosomatic Medicine
81
發行號3
DOIs
出版狀態已發佈 - 四月 2019

指紋

Spasm
Coronary Vessels
Anxiety
Depression
Coronary Artery Disease
Population
Odds Ratio
Confidence Intervals
Propensity Score
Control Groups
National Health Programs
Taiwan
Sex Characteristics
Databases

引用此文

Coronary Artery Spasm as Related to Anxiety and Depression : A Nationwide Population-Based Study. / Hung, Ming-Yow; Mao, Chun-Tai; Hung, Ming-Jui; Wang, Jiunn-Kae; Lee, Hsin-Chien; Yeh, Chi-Tai; Hu, Patrick; Chen, Tien-Hsing; Chang, Nen-Chung.

於: Psychosomatic Medicine, 卷 81, 編號 3, 04.2019, p. 237-245.

研究成果: 雜誌貢獻文章

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title = "Coronary Artery Spasm as Related to Anxiety and Depression: A Nationwide Population-Based Study",
abstract = "OBJECTIVE: Anxiety and depression are risk factors for obstructive coronary artery disease (CAD), but their effects on coronary artery spasm (CAS) remain unestablished.METHODS: Patient records in this population-based study were retrospectively collected from the Taiwan National Health Insurance Research Database. Using propensity score matching, we used 1:1:1 ratio stratification into a control group of 10,325 individuals without CAS or CAD, a CAS group comprising 10,473 patients, and a CAD group comprising 10,473 patients during 2000-2012.RESULTS: The prevalence of CAS and CAD was 0.067{\%} and 8.7{\%}, respectively, in the general population. The prevalence of anxiety and depression diagnoses was significantly higher in patients with new-onset CAS than in those with new-onset CAD and controls without CAS/CAD, even after propensity score matching. Compared with CAD, anxiety and depression diagnoses conferred a higher risk of developing CAS (odds ratio [OR] = 2.29, 95{\%} confidence interval [CI], 2.14-2.45, p < .001, and OR = 1.34, 95{\%} CI, 1.08-1.66, p = .007, respectively). The association was even stronger when comparing CAS with the control group without CAD or CAS (OR = 5.20, 95{\%} CI, 4.72-5.74, p < .001, and OR = 1.98, 95{\%} CI, 1.50-2.62, p < .001, respectively). The increased risk of new-onset CAS as related to previous anxiety and depression diagnoses was comparable between males and females.CONCLUSIONS: Compared with CAD or the general population, anxiety and depression diagnoses confer a higher risk of developing CAS. No sex differences are found for the association of anxiety and depression with CAS.",
author = "Ming-Yow Hung and Chun-Tai Mao and Ming-Jui Hung and Jiunn-Kae Wang and Hsin-Chien Lee and Chi-Tai Yeh and Patrick Hu and Tien-Hsing Chen and Nen-Chung Chang",
year = "2019",
month = "4",
doi = "10.1097/PSY.0000000000000666",
language = "English",
volume = "81",
pages = "237--245",
journal = "Psychosomatic Medicine",
issn = "0033-3174",
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TY - JOUR

T1 - Coronary Artery Spasm as Related to Anxiety and Depression

T2 - A Nationwide Population-Based Study

AU - Hung, Ming-Yow

AU - Mao, Chun-Tai

AU - Hung, Ming-Jui

AU - Wang, Jiunn-Kae

AU - Lee, Hsin-Chien

AU - Yeh, Chi-Tai

AU - Hu, Patrick

AU - Chen, Tien-Hsing

AU - Chang, Nen-Chung

PY - 2019/4

Y1 - 2019/4

N2 - OBJECTIVE: Anxiety and depression are risk factors for obstructive coronary artery disease (CAD), but their effects on coronary artery spasm (CAS) remain unestablished.METHODS: Patient records in this population-based study were retrospectively collected from the Taiwan National Health Insurance Research Database. Using propensity score matching, we used 1:1:1 ratio stratification into a control group of 10,325 individuals without CAS or CAD, a CAS group comprising 10,473 patients, and a CAD group comprising 10,473 patients during 2000-2012.RESULTS: The prevalence of CAS and CAD was 0.067% and 8.7%, respectively, in the general population. The prevalence of anxiety and depression diagnoses was significantly higher in patients with new-onset CAS than in those with new-onset CAD and controls without CAS/CAD, even after propensity score matching. Compared with CAD, anxiety and depression diagnoses conferred a higher risk of developing CAS (odds ratio [OR] = 2.29, 95% confidence interval [CI], 2.14-2.45, p < .001, and OR = 1.34, 95% CI, 1.08-1.66, p = .007, respectively). The association was even stronger when comparing CAS with the control group without CAD or CAS (OR = 5.20, 95% CI, 4.72-5.74, p < .001, and OR = 1.98, 95% CI, 1.50-2.62, p < .001, respectively). The increased risk of new-onset CAS as related to previous anxiety and depression diagnoses was comparable between males and females.CONCLUSIONS: Compared with CAD or the general population, anxiety and depression diagnoses confer a higher risk of developing CAS. No sex differences are found for the association of anxiety and depression with CAS.

AB - OBJECTIVE: Anxiety and depression are risk factors for obstructive coronary artery disease (CAD), but their effects on coronary artery spasm (CAS) remain unestablished.METHODS: Patient records in this population-based study were retrospectively collected from the Taiwan National Health Insurance Research Database. Using propensity score matching, we used 1:1:1 ratio stratification into a control group of 10,325 individuals without CAS or CAD, a CAS group comprising 10,473 patients, and a CAD group comprising 10,473 patients during 2000-2012.RESULTS: The prevalence of CAS and CAD was 0.067% and 8.7%, respectively, in the general population. The prevalence of anxiety and depression diagnoses was significantly higher in patients with new-onset CAS than in those with new-onset CAD and controls without CAS/CAD, even after propensity score matching. Compared with CAD, anxiety and depression diagnoses conferred a higher risk of developing CAS (odds ratio [OR] = 2.29, 95% confidence interval [CI], 2.14-2.45, p < .001, and OR = 1.34, 95% CI, 1.08-1.66, p = .007, respectively). The association was even stronger when comparing CAS with the control group without CAD or CAS (OR = 5.20, 95% CI, 4.72-5.74, p < .001, and OR = 1.98, 95% CI, 1.50-2.62, p < .001, respectively). The increased risk of new-onset CAS as related to previous anxiety and depression diagnoses was comparable between males and females.CONCLUSIONS: Compared with CAD or the general population, anxiety and depression diagnoses confer a higher risk of developing CAS. No sex differences are found for the association of anxiety and depression with CAS.

U2 - 10.1097/PSY.0000000000000666

DO - 10.1097/PSY.0000000000000666

M3 - Article

VL - 81

SP - 237

EP - 245

JO - Psychosomatic Medicine

JF - Psychosomatic Medicine

SN - 0033-3174

IS - 3

ER -