Continuous veno-venous hemofiltration yields better renal outcomes than intermittent hemodialysis among traumatic intracranial hemorrhage patients with acute kidney injury: A nationwide population-based retrospective study in Taiwan

Min Feng Tseng, Chu Lin Chou, Chi Hsiang Chung, Wu Chien Chien, Ying Kai Chen, Hsiu Chien Yang, Chen Yi Liao, Kuang Yu Wei, Chia Chao Wu

研究成果: 雜誌貢獻文章

摘要

Object Traumatic intracranial hemorrhage (TICH) patients with acute kidney injury (AKI) were reported to have a high mortality rate. Renal replacement therapy (RRT) is indicated for patients with a severe kidney injury. This study aimed to compare the effects of different RRT modalities regarding chronic dialysis rate among adult TICH patients with AKI. Methods A retrospective search of computerized hospital records from 2000 to 2010 for patients with a discharge diagnosis of TICH was conducted to identify the index cases. We collected the data of TICH patients with increased intracranial pressure combined with severe AKI who received intermittent hemodialysis (IHD) or continuous veno-venous hemofiltration (CVVH) as RRT. The outcome was dialysis dependence between 2000 and 2010. Results From a total of 310 patients who were enrolled in the study, 134 (43%) received CVVH and 176 (57%) received IHD. The risk of dialysis dependency was significantly lower in the CVVH group than in the IHD group (adjusted hazard ratio: 0.368, 95% CI, 0.158–0.858, P = 0.034). Diabetes mellitus and coronary artery disease were risk factors for dialysis dependency. CVVH compared with IHD modality was associated with lower dialysis dependency rate in TICH patients combined with AKI and diabetes mellitus and those with an injury severity score (ISS) 16. Conclusion CVVH may yield better renal outcomes than IHD among TICH patients with AKI, especially those with diabetes mellitus and an ISS 16. The beneficial impact of CVVH on TICH patients needs to be clarified in a large cohort study in future.
原文英語
文章編號e0203088
期刊PLoS One
13
發行號9
DOIs
出版狀態已發佈 - 九月 1 2018

指紋

Traumatic Intracranial Hemorrhage
Hemofiltration
hemodialysis
Dialysis
Taiwan
Acute Kidney Injury
retrospective studies
hemorrhage
Renal Dialysis
Retrospective Studies
kidneys
Kidney
Medical problems
dialysis
Population
Renal Replacement Therapy
diabetes mellitus
Diabetes Mellitus
Injury Severity Score
therapeutics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

引用此文

Continuous veno-venous hemofiltration yields better renal outcomes than intermittent hemodialysis among traumatic intracranial hemorrhage patients with acute kidney injury : A nationwide population-based retrospective study in Taiwan. / Tseng, Min Feng; Chou, Chu Lin; Chung, Chi Hsiang; Chien, Wu Chien; Chen, Ying Kai; Yang, Hsiu Chien; Liao, Chen Yi; Wei, Kuang Yu; Wu, Chia Chao.

於: PLoS One, 卷 13, 編號 9, e0203088, 01.09.2018.

研究成果: 雜誌貢獻文章

Tseng, Min Feng ; Chou, Chu Lin ; Chung, Chi Hsiang ; Chien, Wu Chien ; Chen, Ying Kai ; Yang, Hsiu Chien ; Liao, Chen Yi ; Wei, Kuang Yu ; Wu, Chia Chao. / Continuous veno-venous hemofiltration yields better renal outcomes than intermittent hemodialysis among traumatic intracranial hemorrhage patients with acute kidney injury : A nationwide population-based retrospective study in Taiwan. 於: PLoS One. 2018 ; 卷 13, 編號 9.
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abstract = "Object Traumatic intracranial hemorrhage (TICH) patients with acute kidney injury (AKI) were reported to have a high mortality rate. Renal replacement therapy (RRT) is indicated for patients with a severe kidney injury. This study aimed to compare the effects of different RRT modalities regarding chronic dialysis rate among adult TICH patients with AKI. Methods A retrospective search of computerized hospital records from 2000 to 2010 for patients with a discharge diagnosis of TICH was conducted to identify the index cases. We collected the data of TICH patients with increased intracranial pressure combined with severe AKI who received intermittent hemodialysis (IHD) or continuous veno-venous hemofiltration (CVVH) as RRT. The outcome was dialysis dependence between 2000 and 2010. Results From a total of 310 patients who were enrolled in the study, 134 (43{\%}) received CVVH and 176 (57{\%}) received IHD. The risk of dialysis dependency was significantly lower in the CVVH group than in the IHD group (adjusted hazard ratio: 0.368, 95{\%} CI, 0.158–0.858, P = 0.034). Diabetes mellitus and coronary artery disease were risk factors for dialysis dependency. CVVH compared with IHD modality was associated with lower dialysis dependency rate in TICH patients combined with AKI and diabetes mellitus and those with an injury severity score (ISS) 16. Conclusion CVVH may yield better renal outcomes than IHD among TICH patients with AKI, especially those with diabetes mellitus and an ISS 16. The beneficial impact of CVVH on TICH patients needs to be clarified in a large cohort study in future.",
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T1 - Continuous veno-venous hemofiltration yields better renal outcomes than intermittent hemodialysis among traumatic intracranial hemorrhage patients with acute kidney injury

T2 - A nationwide population-based retrospective study in Taiwan

AU - Tseng, Min Feng

AU - Chou, Chu Lin

AU - Chung, Chi Hsiang

AU - Chien, Wu Chien

AU - Chen, Ying Kai

AU - Yang, Hsiu Chien

AU - Liao, Chen Yi

AU - Wei, Kuang Yu

AU - Wu, Chia Chao

PY - 2018/9/1

Y1 - 2018/9/1

N2 - Object Traumatic intracranial hemorrhage (TICH) patients with acute kidney injury (AKI) were reported to have a high mortality rate. Renal replacement therapy (RRT) is indicated for patients with a severe kidney injury. This study aimed to compare the effects of different RRT modalities regarding chronic dialysis rate among adult TICH patients with AKI. Methods A retrospective search of computerized hospital records from 2000 to 2010 for patients with a discharge diagnosis of TICH was conducted to identify the index cases. We collected the data of TICH patients with increased intracranial pressure combined with severe AKI who received intermittent hemodialysis (IHD) or continuous veno-venous hemofiltration (CVVH) as RRT. The outcome was dialysis dependence between 2000 and 2010. Results From a total of 310 patients who were enrolled in the study, 134 (43%) received CVVH and 176 (57%) received IHD. The risk of dialysis dependency was significantly lower in the CVVH group than in the IHD group (adjusted hazard ratio: 0.368, 95% CI, 0.158–0.858, P = 0.034). Diabetes mellitus and coronary artery disease were risk factors for dialysis dependency. CVVH compared with IHD modality was associated with lower dialysis dependency rate in TICH patients combined with AKI and diabetes mellitus and those with an injury severity score (ISS) 16. Conclusion CVVH may yield better renal outcomes than IHD among TICH patients with AKI, especially those with diabetes mellitus and an ISS 16. The beneficial impact of CVVH on TICH patients needs to be clarified in a large cohort study in future.

AB - Object Traumatic intracranial hemorrhage (TICH) patients with acute kidney injury (AKI) were reported to have a high mortality rate. Renal replacement therapy (RRT) is indicated for patients with a severe kidney injury. This study aimed to compare the effects of different RRT modalities regarding chronic dialysis rate among adult TICH patients with AKI. Methods A retrospective search of computerized hospital records from 2000 to 2010 for patients with a discharge diagnosis of TICH was conducted to identify the index cases. We collected the data of TICH patients with increased intracranial pressure combined with severe AKI who received intermittent hemodialysis (IHD) or continuous veno-venous hemofiltration (CVVH) as RRT. The outcome was dialysis dependence between 2000 and 2010. Results From a total of 310 patients who were enrolled in the study, 134 (43%) received CVVH and 176 (57%) received IHD. The risk of dialysis dependency was significantly lower in the CVVH group than in the IHD group (adjusted hazard ratio: 0.368, 95% CI, 0.158–0.858, P = 0.034). Diabetes mellitus and coronary artery disease were risk factors for dialysis dependency. CVVH compared with IHD modality was associated with lower dialysis dependency rate in TICH patients combined with AKI and diabetes mellitus and those with an injury severity score (ISS) 16. Conclusion CVVH may yield better renal outcomes than IHD among TICH patients with AKI, especially those with diabetes mellitus and an ISS 16. The beneficial impact of CVVH on TICH patients needs to be clarified in a large cohort study in future.

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