Construct logic operation gates of OR and and with multiple enzymes

Chu Yuyi, Juiyu Wu, Junzo Watada, Ikno Kim

研究成果: 書貢獻/報告類型會議貢獻

摘要

Biomoleculars act as a tool to build a multiple enzyme system based on human metabolic actions to perform basic logic operation connecting OR and AND gates. Three enzymes (invertase, amyloglucosidase, hexokinase) concert as a logic operation part, processing three molecular input signals (sucrose, maltose, and ATP) to produce G6P (glucose-6-phosphate). The other two enzymes glucose-6-phosphate dehydrogenase (G6PD) and salicylate hydroxylase (SHL) compose to function as a signal displayer. Furthermore, we used a latent fluorescent molecule composed of sacylate and fluorescence which can be catalyzed and release fluorescent molecular to produce output signal. According to our experiments, firstly, our design is proved. The typical characteristics of enzyme reactions have been discovered through comparing the expected theoretical cures with the result cures. Secondly, the possibility of applying multiple logic gates into complicate networks has been shown.

原文英語
主出版物標題Proceedings - 4th International Conference on Genetic and Evolutionary Computing, ICGEC 2010
頁面35-38
頁數4
DOIs
出版狀態已發佈 - 2010
事件4th International Conference on Genetic and Evolutionary Computing, ICGEC 2010 - Shenzhen, 中国
持續時間: 十二月 13 2010十二月 15 2010

其他

其他4th International Conference on Genetic and Evolutionary Computing, ICGEC 2010
國家中国
城市Shenzhen
期間12/13/1012/15/10

ASJC Scopus subject areas

  • Computational Theory and Mathematics
  • Theoretical Computer Science

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  • 引用此

    Yuyi, C., Wu, J., Watada, J., & Kim, I. (2010). Construct logic operation gates of OR and and with multiple enzymes. 於 Proceedings - 4th International Conference on Genetic and Evolutionary Computing, ICGEC 2010 (頁 35-38). [5715364] https://doi.org/10.1109/ICGEC.2010.17